Search Count: 21
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Crystal Structure Of The Hepatitis C Virus Genotype 2A Strain Jfh1 Ns5B Rna-Dependent Rna Polymerase In Complex With 6-[Ethyl(Methylsulfonyl)Amino]-2-(4-Fluorophenyl)-N-Methyl-5-(3-{[1-(Pyrimidin-2-Yl)Cyclopropyl]Carbamoyl}Phenyl)-1-Benzofuran-3-Carboxamide
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION Resolution:2.08 Å Release Date: 2018-11-21 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: J6D, SCN, 2PE, GOL |
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION
Release Date: 2018-11-21
Ligands: J6D, SCN, 2PE, GOL
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Crystal Structure Of The Hepatitis C Virus Genotype 2A Strain Jfh1 L30S Ns5B Rna-Dependent Rna Polymerase In Complex With 6-(Ethylamino)-2-(4-Fluorophenyl)-5-(3-{[1-(5-Fluoropyrimidin-2-Yl)Cyclopropyl]Carbamoyl}-4-Methoxyphenyl)-N-Methyl-1-Benzofuran-3-Carboxamide
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2018-11-21 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: J6J, SO4, GOL, PG4 |
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION
Release Date: 2018-11-21
Ligands: J6J, SO4, GOL, PG4
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase In Complex With 2-(4-Fluorophenyl)-N-Methyl-6-[(Methylsulfonyl)Amino]-5-(Propan-2-Yloxy)-1-Benzofuran-3-Carboxamide
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2017-05-10 Classification: TRANSFERASE Ligands: 23E, 2N5, SO4, GOL, PG4 |
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION
Release Date: 2017-05-10
Ligands: 23E, 2N5, SO4, GOL, PG4
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase In Complex With 2-({3-[1-(2-Cyclopropylethyl)-6-Fluoro-4-Hydroxy-2-Oxo-1,2-Dihydroquinolin-3-Yl]-1,1-Dioxo-1,4-Dihydro-1Lambda~6~,2,4-Benzothiadiazin-7-Yl}Oxy)Acetamide
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION Resolution:2.06 Å Release Date: 2017-05-10 Classification: TRANSFERASE Ligands: 23E, 8XV, SO4 |
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION
Release Date: 2017-05-10
Ligands: 23E, 8XV, SO4
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase In Complex With 3-[2-(4-Fluorophenyl)-3-(Methylcarbamoyl)-1-Benzofuran-5-Yl]Benzoic Acid
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION Resolution:2.54 Å Release Date: 2017-05-10 Classification: TRANSFERASE Ligands: 23E, SO4, 8XS, GOL |
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION
Release Date: 2017-05-10
Ligands: 23E, SO4, 8XS, GOL
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase In Complex With 5-[3-(Tert-Butylcarbamoyl)Phenyl]-2-(4-Fluorophenyl)-N-Methyl-1-Benzofuran-3-Carboxamide
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2017-05-10 Classification: TRANSFERASE Ligands: 23E, 8XP, SO4, GOL |
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION
Release Date: 2017-05-10
Ligands: 23E, 8XP, SO4, GOL
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase C316N In Complex With 2-(4-Fluorophenyl)-N-Methyl-5-[3-({2-Methyl-1-Oxo-1-[(1,3,4-Thiadiazol-2-Yl)Amino]Propan-2-Yl}Carbamoyl)Phenyl]-1-Benzofuran-3-Carboxamide
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2017-05-10 Classification: TRANSFERASE Ligands: 23E, 8XM, SO4, GOL |
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION
Release Date: 2017-05-10
Ligands: 23E, 8XM, SO4, GOL
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase In Complex With 4-Fluoro-2-(4-Fluorophenyl)-N-Methyl-5-(2-Methyl-5-{[1-(Pyrimidin-2-Yl)Cyclopropyl]Carbamoyl}Phenyl)-1-Benzofuran-3-Carboxamide (Bms-929075)
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION Resolution:2.95 Å Release Date: 2017-05-10 Classification: TRANSFERASE Ligands: 23E, 8XJ, SO4, GOL |
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION
Release Date: 2017-05-10
Ligands: 23E, 8XJ, SO4, GOL
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Crystal Structure Of The Hepatitis C Virus Genotype 2A Strain Jfh1 L30S Ns5B Rna-Dependent Rna Polymerase In Complex With 5-[3-(Tert-Butylcarbamoyl)Phenyl]-6-(Ethylamino)-2-(4-Fluorophenyl)-N-Methylfuro[2,3-B]Pyridine-3-Carboxamide
Organism: Hepatitis c virus genotype 2a (isolate jfh-1)
Method: X-RAY DIFFRACTION Resolution:1.97 Å Release Date: 2017-03-15 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: 7NG, SO4, PE5, PG4 |
Organism: Hepatitis c virus genotype 2a (isolate jfh-1)
Method: X-RAY DIFFRACTION
Release Date: 2017-03-15
Ligands: 7NG, SO4, PE5, PG4
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna- Dependent Rna Polymerase In Complex With 5-[3-(Tert-Butylcarbamoyl)Phenyl]-6-(Ethylamino)-2-(4-Fluorophenyl)-N-Methylfuro[2,3-B]Pyridine-3-Carboxamide
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION Resolution:3.04 Å Release Date: 2017-03-15 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: 23E, SO4, 7NG |
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION
Release Date: 2017-03-15
Ligands: 23E, SO4, 7NG
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase Complex With Bms-791325 Also Known As (1Ar,12Bs)-8-Cyclohexyl-N-(Dimethylsulfamoyl)-11-Methoxy-1A-{[(1R,5S)-3-Methyl-3,8-Diazabicyclo[3.2.1]Oct-8-Yl]Carbonyl}-1,1A,2,12B-Tetrahydrocyclopropa[D]Indolo[2,1-A][2]Benzazepine-5-Carboxamide And 2-(4-Fluorophenyl)-N-Methyl-6-[(Methylsulfonyl)Amino]-5-(Propan-2-Yloxy)-1-Benzofuran-3-Carboxamide
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION Resolution:2.75 Å Release Date: 2014-03-19 Classification: transferase/transferase INHIBITOR Ligands: 2N7, 2N5, SO4, BOG |
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION
Release Date: 2014-03-19
Ligands: 2N7, 2N5, SO4, BOG
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase Complex With (2E)-3-(4-{[(1-{[(13-Cyclohexyl-6-Oxo-6,7-Dihydro-5H-Indolo[1,2-D][1,4]Benzodiazepin-10-Yl)Carbonyl]Amino}Cyclopentyl)Carbonyl]Amino}Phenyl)Prop-2-Enoic Acid
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION Resolution:2.29 Å Release Date: 2011-04-27 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 23E, SO4 |
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION
Release Date: 2011-04-27
Ligands: 23E, SO4
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase Complex With (2E)-3-(4-{[(1-{[(13-Cyclohexyl-6-Oxo-6,7-Dihydro-5H-Indolo[1,2-D][1,4]Benzodiazepin-10-Yl)Carbonyl]Amino}Cyclopentyl)Carbonyl]Amino}Phenyl)Prop-2-Enoic Acid And (2R)-4-(2,6-Dimethoxypyrimidin-4-Yl)-1-[(4-Ethylphenyl)Sulfonyl]-N-(4-Methoxybenzyl)Piperazine-2-Carboxamide
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2011-04-20 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 23E, SO4, 26S |
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION
Release Date: 2011-04-20
Ligands: 23E, SO4, 26S
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase Complex With (2E)-3-(4-{[(1-{[(13-Cyclohexyl-6-Oxo-6,7-Dihydro-5H-Indolo[1,2-D][1,4]Benzodiazepin-10-Yl)Carbonyl]Amino}Cyclopentyl)Carbonyl]Amino}Phenyl)Prop-2-Enoic Acid And (2R)-4-(2,6-Dimethoxypyrimidin-4-Yl)-N-(4-Methoxybenzyl)-1-{[4-(Trifluoromethoxy)Phenyl]Sulfonyl}Piperazine-2-Carboxamide
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2011-04-20 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 23E, SO4, 26F |
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION
Release Date: 2011-04-20
Ligands: 23E, SO4, 26F
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase Complex With (2E)-3-(4-{[(1-{[(13-Cyclohexyl-6-Oxo-6,7-Dihydro-5H-Indolo[1,2-D][1,4]Benzodiazepin-10-Yl)Carbonyl]Amino}Cyclopentyl)Carbonyl]Amino}Phenyl)Prop-2-Enoic Acid And (2R)-4-(6-Chloropyridazin-3-Yl)-N-(4-Methoxybenzyl)-1-{[4-(Trifluoromethoxy)Phenyl]Sulfonyl}Piperazine-2-Carboxamide
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2011-04-20 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 23E, 46F, SO4 |
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION
Release Date: 2011-04-20
Ligands: 23E, 46F, SO4
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase Complex With (2E)-3-(4-{[(1-{[(13-Cyclohexyl-6-Oxo-6,7-Dihydro-5H-Indolo[1,2-D][1,4]Benzodiazepin-10-Yl)Carbonyl]Amino}Cyclopentyl)Carbonyl]Amino}Phenyl)Prop-2-Enoic Acid And N-Cyclopropyl-6-[(3R)-3-{[4-(Trifluoromethoxy)Benzyl]Carbamoyl}-4-{[4-(Trifluoromethoxy)Phenyl]Sulfonyl}Piperazin-1-Yl]Pyridazine-3-Carboxamide
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION Resolution:3.22 Å Release Date: 2011-04-20 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 23E, 63F, SO4 |
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION
Release Date: 2011-04-20
Ligands: 23E, 63F, SO4
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase Genotype 1A Complex With N-Cyclopropyl-6-[(3R)-3-{[4-(Trifluoromethoxy)Benzyl]Carbamoyl}-4-{[4-(Trifluoromethoxy)Phenyl]Sulfonyl}Piperazin-1-Yl]Pyridazine-3-Carboxamide
Organism: Hepatitis c virus subtype 1a
Method: X-RAY DIFFRACTION Resolution:2.14 Å Release Date: 2011-04-20 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 63F, PO4 |
Organism: Hepatitis c virus subtype 1a
Method: X-RAY DIFFRACTION
Release Date: 2011-04-20
Ligands: 63F, PO4
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase Genotype 1A Complex With N-[(2S)-Butan-2-Yl]-6-[(3R)-3-{[4-(Trifluoromethoxy)Benzyl]Carbamoyl}-4-{[4-(Trifluoromethoxy)Phenyl]Sulfonyl}Piperazin-1-Yl]Pyridazine-3-Carboxamide
Organism: Hepatitis c virus subtype 1a
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2011-04-20 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 33F, GOL |
Organism: Hepatitis c virus subtype 1a
Method: X-RAY DIFFRACTION
Release Date: 2011-04-20
Ligands: 33F, GOL
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Engrailed Homeodomain Q50A Variant Dna Complex
Organism: Drosophila melanogaster
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2000-07-31 Classification: TRANSCRIPTION/DNA |
Organism: Drosophila melanogaster
Method: X-RAY DIFFRACTION
Release Date: 2000-07-31
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Crystal Structure Of The Oct-1 Pou Domain Bound To An Octamer Site: Dna Recognition With Tethered Dna-Binding Modules
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 1994-08-31 Classification: TRANSCRIPTION/DNA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 1994-08-31