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Structure Of Kras-G12C Bound To 1-[(4Ar,10P,13R)-10-[5-Amino-4-Fluoro-3-Methyl-2-(Trifluoromethyl)Phenyl]-11-Chloro-9-Fluoro-1,2,4A,5-Tetrahydropyrazino[1',2':4,5][1,4]Oxazino[2,3-C]Quinolin-3(4H)-Yl]Prop-2-En-1-One (Compound 15)
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: MG, GDP, A1CII, PEG, GOL, DMS, ACT |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: A1CQ2, GDP, MG |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: GDP, MG, DMS, EDO, A1AWR, PEG |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.99 Å Release Date: 2026-01-28 Classification: IMMUNE SYSTEM Ligands: EOH, GOL, SO4, A1CU3 |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.76 Å Release Date: 2026-01-28 Classification: IMMUNE SYSTEM Ligands: GOL, EOH, MG, A1CWM, SO4 |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.97 Å Release Date: 2026-01-28 Classification: IMMUNE SYSTEM Ligands: EOH, A1CWL, SO4, GOL, MG |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.26 Å Release Date: 2026-01-28 Classification: IMMUNE SYSTEM Ligands: CL, EDO, GOL, A1CWK, MG |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2026-01-28 Classification: IMMUNE SYSTEM Ligands: EDO, NA, MG |
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Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2023-06-07 Classification: SIGNALING PROTEIN Ligands: SO4, DYQ |