Search Count: 263
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Structure Of Human Ulk1C:Pi3Kc3-C1 Supercomplex
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2024-07-03 Classification: IMMUNE SYSTEM |
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Co-Crystal Structure Of Lipid Kinase Pi3K Alpha With A Selective Phosphatidylinositol-3 Kinase Alpha Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.62 Å Release Date: 2016-05-18 Classification: transferase/transferase inhibitor Ligands: 4Q2 |
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Pi3Kc3-C1 In Complex With Rab1A. Vps34 Kinase Domain Active Conformation
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: GTP, MG |
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Cryo Em Reconstruction Of Pi3Kc3-C1 In Complex With Human Rab1A(Q70L), Vps34 Kinase Domain In The Inactive Conformation
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: GTP, MG, MYR |
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Co-Crystal Structures Of The Lipid Kinase Pi3K Alpha With Pan And Isoform Selective Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2014-04-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SCN, 1LT |
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Crystal Structure Of Human T1061E Pi3Kalpha In Complex With Its Regulatory Subunit And The Inhibitor Gdc-0077 (Inavolisib)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.82 Å Release Date: 2023-12-13 Classification: TRANSFERASE Ligands: MWF, EDO, PGE, CL |
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Crystal Structure Of Vps34 In Complex With Sar405.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2014-10-22 Classification: LIPID KINASE Ligands: SO4, 1TT |
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Human Complex Ii-Bats Bound To Membrane-Attached Rab5A-Gtp
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2026-06-03 Classification: ENDOCYTOSIS Ligands: MYR, GDP, MG, ZN, GTP |
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Co-Structure Of Phosphatidylinositol 4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha Isoform And Brain Penetrant Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2023-07-19 Classification: TRANSFERASE Ligands: ZTV, SO4 |
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Co-Structure Phosphatidylinositol 4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha Isoform Complexed With Brain Penetrant Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.10 Å Release Date: 2023-07-19 Classification: TRANSFERASE Ligands: ZUO |
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Crystal Structure Of P110Alpha In Complex With Ish2 Of P85Alpha And The Inhibitor Pik-108
Organism: Mus musculus, Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.50 Å Release Date: 2011-12-28 Classification: TRANSFERASE Ligands: P08 |
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Cryo-Em Reconstruction Of Pi3Kc3-C1 In Complex With Human Rab1A(Q70L)
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: GTP, MG, MYR |
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Vps34-Cii (Vps34 199-Reie-202 To 199-Aaaa-202 Mutant) Bound To Rab5A (Q79L)
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2026-06-03 Classification: ENDOCYTOSIS Ligands: MYR, GDP, MG, ZN, GTP |
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Vps34-Cii (Vps34 199-Reie-202 To 199-Erir-202 Mutant) Bound To Rab5A (Q79L) On The Vps15 Subunit
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2026-06-03 Classification: ENDOCYTOSIS Ligands: MYR, GDP, MG, ZN, GTP |
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Apo Vps34-Cii (Vps34/Vps15/Beclin1/Uvrag)
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2026-06-03 Classification: ENDOCYTOSIS Ligands: GDP, MG, MYR, ZN |
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Vps34-Cii (Vps34/Vps15/Beclin1/Uvrag) Bound To Rab5A (Q79L) On The Vps34 And Vps15 Subunits
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2026-06-03 Classification: ENDOCYTOSIS Ligands: GDP, MG, MYR, ZN, GTP |
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Vps34-Cii Bound To Rab5A-Gtp 1-212 (C19S, C63S, Q79L) On The Vps34 Subunit
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2026-06-03 Classification: ENDOCYTOSIS Ligands: GDP, MG, MYR, ZN, GTP |
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Vps34-Cii Bound To Rab5A-Gtp 1-212 (C19S, C63S, Q79L) On The Vps15 Subunit
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2026-06-03 Classification: ENDOCYTOSIS Ligands: GDP, MG, MYR, ZN, GTP |
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Cryoem Structure Of Human Pi3K-Alpha (P85/P110-H1047R) With Qr-7909 Binding At An Allosteric Site
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2024-04-17 Classification: ONCOPROTEIN Ligands: UEX |
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Cryoem Structure Of Human Pi3K-Alpha (P85/P110-H1047R) With Qr-8557 Binding At An Allosteric Site
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2024-04-17 Classification: ONCOPROTEIN Ligands: UJ3 |