ISDA: 9RX4

Deposition Date 2025-07-10

Release Date 2026-07-22

Last Version Date 2026-07-22

Entry Detail

PDB ID:

9RX4

Keywords:

SIGNALING PROTEIN

Title:

VPS34-CI bound to NRBF2 and RAB1A

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens, Escherichia coli bl21(de3), Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.67 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Phosphatidylinositol 3-kinase
Gene (Uniprot):PIK3C3
Chain IDs:A
Chain Length:887
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q8NEB9 Pfam ID:PF00792, PF00613, PF00454 EC:2.7.1.137

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Phosphoinositide 3-kinase reg
Gene (Uniprot):PIK3R4
Chain IDs:B
Chain Length:1370
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q99570 Pfam ID:PF00069, PF22956, PF00400 EC:2.7.11.1

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Beclin-1
Gene (Uniprot):BECN1
Chain IDs:C, F (auth: I)
Chain Length:450
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q14457 Pfam ID:PF15285, PF17675, PF04111

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Beclin 1-associated autophagy
Gene (Uniprot):ATG14
Mutagens:N256S, insertion of T after M1
Chain IDs:D
Chain Length:493
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q6ZNE5 Pfam ID:PF10186 EC:2.7.1.137

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Ras-related protein Rab-1A
Gene (Uniprot):RAB1A
Mutagens:C26S, Q70L, C126S
Chain IDs:E
Chain Length:207
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62820 Pfam ID:PF00071 EC:3.6.5.2

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Nuclear receptor-binding fact
Gene (Uniprot):NRBF2
Chain IDs:G (auth: L)
Chain Length:308
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q96F24 Pfam ID:PF17169, PF08961

Ligand Molecules