Search Count: 34
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Engineering A Tumor-Selective Prodrug T Cell Engager Bispecific Antibody For Safer Immunotherapy
Organism: Mus musculus, Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2024-07-24 Classification: IMMUNE SYSTEM |
Organism: Mus musculus, Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-07-24
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Crystal Structures Of Flap Bound To Dg-031
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.37 Å Release Date: 2020-12-02 Classification: MEMBRANE PROTEIN Ligands: QY1, CA, BOG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-12-02
Ligands: QY1, CA, BOG
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Crystal Structures Of Flap Bound To Mk-866
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.61 Å Release Date: 2020-12-02 Classification: MEMBRANE PROTEIN Ligands: QY7, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-12-02
Ligands: QY7, SO4
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Crystal Structure Of Mpges-1 Bound To Dg-031
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.40 Å Release Date: 2020-12-02 Classification: ISOMERASE, MEMBRANE PROTEIN Ligands: QY1, BOG, PG4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-12-02
Ligands: QY1, BOG, PG4
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Ulk1 Unc-51 Like Autophagy Activating Kinase In Complex With Inhibitor Btc
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.73 Å Release Date: 2019-03-27 Classification: TRANSFERASE/INHIBITOR Ligands: JVD, DMS, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-03-27
Ligands: JVD, DMS, CL
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Crystal Structure Of Mpges-1 Bound To An Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.44 Å Release Date: 2016-04-13 Classification: Isomerase/Isomerase inhibitor Ligands: 4UJ, GSH, JZR, BOG, PGE, PEG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-04-13
Ligands: 4UJ, GSH, JZR, BOG, PGE, PEG
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Discovery Of A Potent And Selective Mpges-1 Inhibitor For The Treatment Of Pain
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2016-04-13 Classification: Isomerase/isomerase inhibitor Ligands: 4UK, GSH, BOG, PG4, 1KA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-04-13
Ligands: 4UK, GSH, BOG, PG4, 1KA
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Discovery Of A Potent And Selective Mpges-1 Inhibitor For The Treatment Of Pain
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.88 Å Release Date: 2016-04-13 Classification: Isomerase/isomerase inhibitor Ligands: 4UL, GSH, BOG, PG4, 1KA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-04-13
Ligands: 4UL, GSH, BOG, PG4, 1KA
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Co-Crystal Structure Of The Hsp90 Atp Binding Domain In Complex With 4-(2,4-Dichloro-5-Methoxyphenyl)-6-Methylpyrimidin-2-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2011-06-08 Classification: CHAPERONE Ligands: 3RP, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-06-08
Ligands: 3RP, PO4
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Co-Crystal Structure Of The Hsp90 Atp Binding Domain In Complex With 4-(2,4-Dichloro-5-Methoxyphenyl)-2-Methyl-7H-Pyrrolo[2,3-D]Pyrimidine-5- Carbonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2011-06-08 Classification: CHAPERONE Ligands: 3RQ, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-06-08
Ligands: 3RQ, PO4
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Co-Crystal Structure Of The Hsp90 Atp Binding Domain In Complex With 4-(2,4-Dichloro-5-Methoxyphenyl)-2,6-Dimethyl-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carbonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2011-06-08 Classification: CHAPERONE Ligands: 3RR, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-06-08
Ligands: 3RR, PO4
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Optimization Of Potent, Selective, And Orally Bioavailable Pyrrolodinopyrimidine-Containing Inhibitors Of Heat Shock Protein 90. Identification Of Development Candidate 2-Amino-4-{4-Chloro-2-[2-(4-Fluoro-1H-Pyrazol-1-Yl)Ethoxy]-6-Methylphenyl}-N-(2,2-Difluoropropyl)-5,7-Dihydro-6H-Pyrrolo[3,4-D]Pyrimidine-6-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2011-04-27 Classification: Chaperone/Chaperone inhibitor Ligands: WOE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-04-27
Ligands: WOE
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Optimization Of Potent, Selective, And Orally Bioavailable Pyrrolodinopyrimidine-Containing Inhibitors Of Heat Shock Protein 90. Identification Of Development Candidate 2-Amino-4-{4-Chloro-2-[2-(4-Fluoro-1H-Pyrazol-1-Yl)Ethoxy]-6-Methylphenyl}-N-(2,2-Difluoropropyl)-5,7-Dihydro-6H-Pyrrolo[3,4-D]Pyrimidine-6-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2011-04-27 Classification: Chaperone/Chaperone inhibitor Ligands: FU5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-04-27
Ligands: FU5
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Optimization Of Potent, Selective, And Orally Bioavailable Pyrrolodinopyrimidine-Containing Inhibitors Of Heat Shock Protein 90. Identification Of Development Candidate 2-Amino-4-{4-Chloro-2-[2-(4-Fluoro-1H-Pyrazol-1-Yl)Ethoxy]-6-Methylphenyl}-N-(2,2-Difluoropropyl)-5,7-Dihydro-6H-Pyrrolo[3,4-D]Pyrimidine-6-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2011-04-27 Classification: Chaperone/Chaperone inhibitor Ligands: FU3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-04-27
Ligands: FU3
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Optimization Of Potent, Selective, And Orally Bioavailable Pyrrolodinopyrimidine-Containing Inhibitors Of Heat Shock Protein 90. Identification Of Development Candidate 2-Amino-4-{4-Chloro-2-[2-(4-Fluoro-1H-Pyrazol-1-Yl)Ethoxy]-6-Methylphenyl}-N-(2,2-Difluoropropyl)-5,7-Dihydro-6H-Pyrrolo[3,4-D]Pyrimidine-6-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2011-04-27 Classification: Chaperone/Chaperone inhibitor Ligands: FU7, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-04-27
Ligands: FU7, PO4
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Hiv-1 Reverse Transcriptase Isolated Rnaseh Domain With The Inhibitor Beta-Thujaplicinol Bound At The Active Site
Organism: Human immunodeficiency virus type 1
Method: X-RAY DIFFRACTION Resolution:2.04 Å Release Date: 2010-02-09 Classification: HYDROLASE Ligands: MN, JTH |
Organism: Human immunodeficiency virus type 1
Method: X-RAY DIFFRACTION
Release Date: 2010-02-09
Ligands: MN, JTH
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Hsp90 N-Terminal Domain In Complex With 4-Chloro-6-{[(2R)-2-(2-Methylphenyl)Pyrrolidin-1-Yl]Carbonyl}Benzene-1,3-Diol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2010-02-09 Classification: CHAPERONE Ligands: 4CD, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-02-09
Ligands: 4CD, DMS
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Hsp90 N-Terminal Domain In Complex With (1R)-2-(5-Chloro-2,4-Dihydroxybenzoyl)-N-Ethylisoindoline-1-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2010-02-09 Classification: CHAPERONE Ligands: 1RC, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-02-09
Ligands: 1RC, PO4
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Hsp90 N-Terminal Domain In Complex With 4-(1,3-Dihydro-2H-Isoindol-2-Ylcarbonyl)Benzene-1,3-Diol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2010-02-09 Classification: CHAPERONE Ligands: PFT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-02-09
Ligands: PFT
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Hiv-1 Reverse Transcriptase With The Inhibitor Beta-Thujaplicinol Bound At The Rnase H Active Site
Organism: Human immunodeficiency virus type 1 bh10
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2010-01-26 Classification: TRANSFERASE Ligands: JTH, MN |
Organism: Human immunodeficiency virus type 1 bh10
Method: X-RAY DIFFRACTION
Release Date: 2010-01-26
Ligands: JTH, MN