Search Count: 99
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Crystal Structure Of Parp1 Catalytic Domain Bound To Azd5305 (Saruparib)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.59 Å Release Date: 2024-12-04 Classification: TRANSFERASE Ligands: A1H63, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-12-04
Ligands: A1H63, SO4
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Crystal Structure Of Parp1 Catalytic Domain Bound To Azd9574
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.82 Å Release Date: 2024-12-04 Classification: TRANSFERASE Ligands: A1H64, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-12-04
Ligands: A1H64, SO4
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Hdac2 In Complex With An Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2022-09-21 Classification: TRANSCRIPTION Ligands: ZN, CA, NA, KIZ, PG4, PEG, KZF |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-09-21
Ligands: ZN, CA, NA, KIZ, PG4, PEG, KZF
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Structure Of Hdac2 Complexed With An Inhibitory Ligand
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.52 Å Release Date: 2022-09-21 Classification: TRANSCRIPTION Ligands: ZN, CA, NA, PGE, EDO, KJ6, 2OP, PG4, PEG, NHE, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-09-21
Ligands: ZN, CA, NA, PGE, EDO, KJ6, 2OP, PG4, PEG, NHE, DMS
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Hdac2 In Complex With Inhibitory Ligand
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2022-09-21 Classification: TRANSCRIPTION Ligands: ZN, CA, NA, EDO, KJN, NHE, PG4, PEG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-09-21
Ligands: ZN, CA, NA, EDO, KJN, NHE, PG4, PEG
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Hdac2 Complexed With An Inhibitory Ligand
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.88 Å Release Date: 2022-09-21 Classification: TRANSCRIPTION Ligands: ZN, CA, NA, PEG, EDO, SHH, KK0, KZF, PG4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-09-21
Ligands: ZN, CA, NA, PEG, EDO, SHH, KK0, KZF, PG4
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Ligand Binding To Hdac2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.56 Å Release Date: 2022-09-21 Classification: TRANSCRIPTION Ligands: ZN, CA, NA, PEG, PGE, KJF, NHE, PG4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-09-21
Ligands: ZN, CA, NA, PEG, PGE, KJF, NHE, PG4, EDO
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Inhibitory Ligand Binding To Hdac2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2022-09-21 Classification: TRANSCRIPTION Ligands: EDO, PG4, PEG, ZN, CA, NA, KKI, NHE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-09-21
Ligands: EDO, PG4, PEG, ZN, CA, NA, KKI, NHE
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Ligand Binding To Hdac2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.73 Å Release Date: 2022-09-21 Classification: TRANSCRIPTION Ligands: PEG, PG4, EDO, ZN, CA, NA, KKW, KZF |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-09-21
Ligands: PEG, PG4, EDO, ZN, CA, NA, KKW, KZF
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Inhibitor Binding To Hdac2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2022-09-21 Classification: TRANSCRIPTION Ligands: ZN, CA, NA, PEG, KRU, NHE, PG4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-09-21
Ligands: ZN, CA, NA, PEG, KRU, NHE, PG4, EDO
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Pyrazole Carboxylic Acid Inhibitors Of Keap1:Nrf2 Interaction
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.89 Å Release Date: 2021-11-17 Classification: PROTEIN BINDING Ligands: DMS, CL, 5UI |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2021-11-17
Ligands: DMS, CL, 5UI
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Pyrazole Carboxylic Acid Inhibitors Of Keap1:Nrf2 Interaction
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.87 Å Release Date: 2021-11-17 Classification: PROTEIN BINDING Ligands: DMS, CL, 5VX |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2021-11-17
Ligands: DMS, CL, 5VX
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Pyrazole Carboxylic Acid Inhibitors Of Keap1:Nrf2 Interaction
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.88 Å Release Date: 2021-11-17 Classification: PROTEIN BINDING Ligands: CL, 5QZ |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2021-11-17
Ligands: CL, 5QZ
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Pyrazole Carboxylic Acid Inhibitors Of Keap1:Nrf2 Interaction
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.86 Å Release Date: 2021-11-17 Classification: PROTEIN BINDING Ligands: CL, SO4, 5X9 |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2021-11-17
Ligands: CL, SO4, 5X9
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Pyrazole Carboxylic Acid Inhibitors Of Keap1:Nrf2 Interaction
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.79 Å Release Date: 2021-11-17 Classification: PROTEIN BINDING Ligands: CL, 5UZ |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2021-11-17
Ligands: CL, 5UZ
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Pyrazole Carboxylic Acid Inhibitors Of Keap1:Nrf2 Interaction
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.89 Å Release Date: 2021-11-17 Classification: PROTEIN BINDING Ligands: CL, 5RQ |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2021-11-17
Ligands: CL, 5RQ
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Pyrazole Carboxylic Acid Inhibitors Of Keap1:Nrf2 Interaction
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2021-11-17 Classification: PROTEIN BINDING Ligands: CL, SO4, 5RB |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2021-11-17
Ligands: CL, SO4, 5RB
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The Structure Of Erk2 In Complex With Dual Inhibitor Astx029
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.76 Å Release Date: 2021-10-06 Classification: SIGNALING PROTEIN Ligands: SO4, DMS, RYW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-10-06
Ligands: SO4, DMS, RYW
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Discovery Of Astx029, A Clinical Candidate Which Modulates The Phosphorylation And Catalytic Activity Of Erk1/2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2021-10-06 Classification: SIGNALING PROTEIN Ligands: SO4, DMS, UMN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-10-06
Ligands: SO4, DMS, UMN
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Discovery Of Astx029, A Clinical Candidate Which Modulates The Phosphorylation And Catalytic Activity Of Erk1/2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.78 Å Release Date: 2021-10-06 Classification: SIGNALING PROTEIN Ligands: SO4, DMS, UNW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-10-06
Ligands: SO4, DMS, UNW