Search Count: 30
 |
Structure Of Kras-G12C Bound To 1-[(4Ar,10P,13R)-10-[5-Amino-4-Fluoro-3-Methyl-2-(Trifluoromethyl)Phenyl]-11-Chloro-9-Fluoro-1,2,4A,5-Tetrahydropyrazino[1',2':4,5][1,4]Oxazino[2,3-C]Quinolin-3(4H)-Yl]Prop-2-En-1-One (Compound 15)
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: MG, GDP, A1CII, PEG, GOL, DMS, ACT |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2026-03-11
Ligands: MG, GDP, A1CII, PEG, GOL, DMS, ACT
 |
An Ester Mutant Of Sfgfp
Organism: Aequorea victoria
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2024-01-17 Classification: FLUORESCENT PROTEIN |
Organism: Aequorea victoria
Method: X-RAY DIFFRACTION
Release Date: 2024-01-17
 |
Kcsa M96V Mutant With Y78Ester In High K+
Organism: Mus musculus, Streptomyces lividans
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2024-01-17 Classification: MEMBRANE PROTEIN Ligands: K, TBA |
Organism: Mus musculus, Streptomyces lividans
Method: X-RAY DIFFRACTION
Release Date: 2024-01-17
Ligands: K, TBA
 |
Kras-G13D-Gdp In Complex With Cpd5 (1-((S)-10-(6-Amino-4-Methyl-3-(Trifluoromethyl)Pyridin-2-Yl)-11-Chloro-7-(((2S,4R)-4-Fluoro-1-Methylpyrrolidin-2-Yl)Methoxy)-3,4,13,13A-Tetrahydropyrazino[2',1':3,4][1,4]Oxazepino[5,6,7-De]Quinazolin-2(1H)-Yl)Prop-2-En-1-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.07 Å Release Date: 2023-12-20 Classification: HYDROLASE,ONCOPROTEIN/INHIBITOR Ligands: XOI, GDP, CL, MG, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-12-20
Ligands: XOI, GDP, CL, MG, EDO
 |
Kras-G13D-Gdp In Complex With Cpd36 ((E)-1-((3S)-4-(7-(6-Amino-4-Methyl-3-(Trifluoromethyl)Pyridin-2-Yl)-6-Chloro-8-Fluoro-2-(((S)-2-Methylenetetrahydro-1H-Pyrrolizin-7A(5H)-Yl)Methoxy)Quinazolin-4-Yl)-3-Methylpiperazin-1-Yl)-3-(4-((Dimethylamino)Methyl)-5-Methylpyridin-2-Yl)Prop-2-En-1-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.57 Å Release Date: 2023-12-20 Classification: HYDROLASE,ONCOPROTEIN/INHIBITOR Ligands: MG, GDP, XV3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-12-20
Ligands: MG, GDP, XV3
 |
Kras-G13D-Gdp In Complex With Cpd38 ((E)-1-((3S)-4-(7-(6-Amino-4-Methyl-3-(Trifluoromethyl)Pyridin-2-Yl)-6-Chloro-8-Fluoro-2-(((S)-2-Methylenetetrahydro-1H-Pyrrolizin-7A(5H)-Yl)Methoxy)Quinazolin-4-Yl)-3-Methylpiperazin-1-Yl)-3-(1,2,3,4-Tetrahydroisoquinolin-8-Yl)Prop-2-En-1-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.31 Å Release Date: 2023-12-20 Classification: HYDROLASE,ONCOPROTEIN/INHIBITOR Ligands: GOL, GDP, MG, XQ6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-12-20
Ligands: GOL, GDP, MG, XQ6
 |
Crystal Structure Of The Dna Preq0 Insertase Dpda
Organism: Salmonella enterica subsp. enterica serovar montevideo
Method: X-RAY DIFFRACTION Resolution:2.51 Å Release Date: 2023-02-22 Classification: DNA BINDING PROTEIN Ligands: ZN |
Organism: Salmonella enterica subsp. enterica serovar montevideo
Method: X-RAY DIFFRACTION
Release Date: 2023-02-22
Ligands: ZN
 |
Crystal Structure Of Htdo2 Bound To Inhibitor Gne1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.18 Å Release Date: 2020-05-06 Classification: OXIDOREDUCTASE/Inhibitor Ligands: HEM, QVY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-05-06
Ligands: HEM, QVY
 |
Dlk In Complex With Compound 10 (5-(1-Isopropyl-5-(3-(Oxetan-3-Yl)-3-Azabicyclo[3.1.0]Hexan-6-Yl)-1H-Pyrazol-3-Yl)-3-(Trifluoromethyl)Pyridin-2-Amine)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2017-10-04 Classification: TRANSFERASE/TRANSFERASE Inhibitor Ligands: 9FS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-10-04
Ligands: 9FS
 |
Dlk In Complex With Inhibitor 5-(1-Isopropyl-5-(1-(Oxetan-3-Yl)Piperidin-4-Yl)-1H-Pyrazol-3-Yl)-3-(Trifluoromethyl)Pyridin-2-Amine (Compound 7)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.96 Å Release Date: 2017-10-04 Classification: TRANSFERASE/TRANSFERASE Inhibitor Ligands: 9FV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-10-04
Ligands: 9FV
 |
Crystal Structure Of Pyrrolidine Amide Inhibitor [(3S)-3-(4-Bromo-1H-Pyrazol-1-Yl)Pyrrolidin-1-Yl][3-(Propan-2-Yl)-1H-Pyrazol-5-Yl]Methanone (Compound 35) In Complex With Kdm5A
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2017-05-10 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NI, ZN, 90S, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-05-10
Ligands: NI, ZN, 90S, SO4
 |
Crystal Structure Of Selective Pyrrolidine Amide Kdm5A Inhibitor N-{(3R)-1-[3-(Propan-2-Yl)-1H-Pyrazole-5-Carbonyl]Pyrrolidin-3-Yl}Cyclopropanecarboxamide (Compound 48)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.05 Å Release Date: 2017-05-10 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NI, ZN, 90V |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-05-10
Ligands: NI, ZN, 90V
 |
Crystal Structure Of Gtp Cyclohydrolase-Ib With 8-Oxo-Gtp
Organism: Neisseria gonorrhoeae (strain atcc 700825 / fa 1090)
Method: X-RAY DIFFRACTION Resolution:2.77 Å Release Date: 2016-09-07 Classification: HYDROLASE, BIOSYNTHETIC PROTEIN Ligands: 8GT, ZN |
Organism: Neisseria gonorrhoeae (strain atcc 700825 / fa 1090)
Method: X-RAY DIFFRACTION
Release Date: 2016-09-07
Ligands: 8GT, ZN
 |
Crystal Structure Of Gtp Cyclohydrolase-Ib With Tris
Organism: Neisseria gonorrhoeae (strain atcc 700825 / fa 1090)
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2016-09-07 Classification: HYDROLASE, BIOSYNTHETIC PROTEIN Ligands: ZN, EDO, TRS, FMT |
Organism: Neisseria gonorrhoeae (strain atcc 700825 / fa 1090)
Method: X-RAY DIFFRACTION
Release Date: 2016-09-07
Ligands: ZN, EDO, TRS, FMT
 |
Kdm4C Bound To Pyrazolo-Pyrimidine Scaffold
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2016-08-17 Classification: OXIDOREDUCTASE Ligands: FE2, ZN, 6X9, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-08-17
Ligands: FE2, ZN, 6X9, CL
 |
Crystal Structure Of Kdm5A In Complex With A Naphthyridone Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.18 Å Release Date: 2016-08-10 Classification: Oxidoreductase/Inhibitor Ligands: NI, ZN, 6QN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-08-10
Ligands: NI, ZN, 6QN
 |
Structure Of The Human Glun1/Glun2A Lbd In Complex With Gne6901
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.09 Å Release Date: 2016-07-13 Classification: TRANSPORT PROTEIN Ligands: ACT, GLU, GLY, 6RM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-07-13
Ligands: ACT, GLU, GLY, 6RM
 |
Structure Of The Human Glun1/Glun2A Lbd In Complex With Gne0723
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.44 Å Release Date: 2016-07-13 Classification: TRANSPORT PROTEIN Ligands: ACT, GLU, 6RV, GLY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-07-13
Ligands: ACT, GLU, 6RV, GLY
 |
Structure Of Histone Lysine Demethylase Kdm5A In Complex With Selective Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.14 Å Release Date: 2016-05-18 Classification: Oxidoreductase/Inhibitor Ligands: NI, ZN, 50P |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-05-18
Ligands: NI, ZN, 50P
 |
Structure Of The Human Glun1/Glun2A Lbd In Complex With 7-{[Ethyl(4-Fluorophenyl)Amino]Methyl}-N,2-Dimethyl-5-Oxo-5H-[1,3]Thiazolo[3,2-A]Pyrimidine-3-Carboxamide (Compound 19)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.86 Å Release Date: 2016-03-16 Classification: TRANSPORT PROTEIN Ligands: GLU, GLY, 67H |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-03-16
Ligands: GLU, GLY, 67H