Search Count: 34
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Targeting Ptpn22 At Non-Orthosteric Binding Sites - A Fragment Approach
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.99 Å Release Date: 2026-01-28 Classification: IMMUNE SYSTEM Ligands: EOH, GOL, SO4, A1CU3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-01-28
Ligands: EOH, GOL, SO4, A1CU3
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Targeting Ptpn22 At Non-Orthosteric Binding Sites - A Fragment Approach
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.76 Å Release Date: 2026-01-28 Classification: IMMUNE SYSTEM Ligands: GOL, EOH, MG, A1CWM, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-01-28
Ligands: GOL, EOH, MG, A1CWM, SO4
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Targeting Ptpn22 At Non-Orthosteric Binding Sites - A Fragment Approach
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.97 Å Release Date: 2026-01-28 Classification: IMMUNE SYSTEM Ligands: EOH, A1CWL, SO4, GOL, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-01-28
Ligands: EOH, A1CWL, SO4, GOL, MG
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Targeting Ptpn22 At Non-Orthosteric Binding Sites - A Fragment Approach
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.26 Å Release Date: 2026-01-28 Classification: IMMUNE SYSTEM Ligands: CL, EDO, GOL, A1CWK, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-01-28
Ligands: CL, EDO, GOL, A1CWK, MG
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Targeting Ptpn22 At Non-Orthosteric Binding Sites - A Fragment Approach
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2026-01-28 Classification: IMMUNE SYSTEM Ligands: EDO, NA, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-01-28
Ligands: EDO, NA, MG
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Crystal Structure Of Inhibitor Gne-6893 Bound To Hpk1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2024-10-02 Classification: SIGNALING PROTEIN Ligands: A1APL, DMS, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-02
Ligands: A1APL, DMS, NA
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Crystal Structure Of Inhibitor 1 Bound To Hpk1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2024-10-02 Classification: SIGNALING PROTEIN Ligands: EDO, A1APO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-02
Ligands: EDO, A1APO
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Crystal Structure Of Inhibitor Gne-6893 Bound To Hpk1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.18 Å Release Date: 2024-10-02 Classification: SIGNALING PROTEIN Ligands: MES, EDO, DMS, A1APR, NA, PEG, A1APQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-02
Ligands: MES, EDO, DMS, A1APR, NA, PEG, A1APQ
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Kras-G13D-Gdp In Complex With Cpd5 (1-((S)-10-(6-Amino-4-Methyl-3-(Trifluoromethyl)Pyridin-2-Yl)-11-Chloro-7-(((2S,4R)-4-Fluoro-1-Methylpyrrolidin-2-Yl)Methoxy)-3,4,13,13A-Tetrahydropyrazino[2',1':3,4][1,4]Oxazepino[5,6,7-De]Quinazolin-2(1H)-Yl)Prop-2-En-1-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.07 Å Release Date: 2023-12-20 Classification: HYDROLASE,ONCOPROTEIN/INHIBITOR Ligands: XOI, GDP, CL, MG, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-12-20
Ligands: XOI, GDP, CL, MG, EDO
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Kras-G13D-Gdp In Complex With Cpd36 ((E)-1-((3S)-4-(7-(6-Amino-4-Methyl-3-(Trifluoromethyl)Pyridin-2-Yl)-6-Chloro-8-Fluoro-2-(((S)-2-Methylenetetrahydro-1H-Pyrrolizin-7A(5H)-Yl)Methoxy)Quinazolin-4-Yl)-3-Methylpiperazin-1-Yl)-3-(4-((Dimethylamino)Methyl)-5-Methylpyridin-2-Yl)Prop-2-En-1-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.57 Å Release Date: 2023-12-20 Classification: HYDROLASE,ONCOPROTEIN/INHIBITOR Ligands: MG, GDP, XV3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-12-20
Ligands: MG, GDP, XV3
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Kras-G13D-Gdp In Complex With Cpd38 ((E)-1-((3S)-4-(7-(6-Amino-4-Methyl-3-(Trifluoromethyl)Pyridin-2-Yl)-6-Chloro-8-Fluoro-2-(((S)-2-Methylenetetrahydro-1H-Pyrrolizin-7A(5H)-Yl)Methoxy)Quinazolin-4-Yl)-3-Methylpiperazin-1-Yl)-3-(1,2,3,4-Tetrahydroisoquinolin-8-Yl)Prop-2-En-1-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.31 Å Release Date: 2023-12-20 Classification: HYDROLASE,ONCOPROTEIN/INHIBITOR Ligands: GOL, GDP, MG, XQ6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-12-20
Ligands: GOL, GDP, MG, XQ6
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Kras G12C In Complex With G-2897
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2022-03-16 Classification: HYDROLASE/Immune System Ligands: Z07, GDP, MG, ACT, CAD, P15, EDO, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: Z07, GDP, MG, ACT, CAD, P15, EDO, DMS
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Crystal Structure Of Kas G12C In Complex With 2H11 Clamp
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2022-03-16 Classification: Hydrolase/Immune System Ligands: GDP, MG, CAC, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: GDP, MG, CAC, EDO
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Crystal Structure Of Gne-1952 Alkylated Kras G12C In Complex With 2H11 Clamp
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2022-03-16 Classification: Hydrolase/Immune System Ligands: MKZ, GDP, MG, GOL, EDO, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: MKZ, GDP, MG, GOL, EDO, SO4
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Crystal Structure Of Kras G12C In Complex With Gne-1952
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2022-03-16 Classification: HYDROLASE Ligands: MKZ, GDP, MG, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: MKZ, GDP, MG, GOL
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Crystal Structure Of Hpk1 In Complex With Compound 2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.33 Å Release Date: 2022-01-05 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2YE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-05
Ligands: 2YE
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Crystal Structure Of Hpk1 In Complex With Gne1858
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2022-01-05 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: F97, EDO, MES |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-05
Ligands: F97, EDO, MES
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Crystal Structure Of Hpk1 In Complex With Compound 14
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2022-01-05 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2WI, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-05
Ligands: 2WI, SO4
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Crystal Structure Of Hpk1 In Complex With Compound 17
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2022-01-05 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2TR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-05
Ligands: 2TR
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Crystal Structure Of Htdo2 Bound To Inhibitor Gne1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.18 Å Release Date: 2020-05-06 Classification: OXIDOREDUCTASE/Inhibitor Ligands: HEM, QVY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-05-06
Ligands: HEM, QVY