Search Count: 26
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Crystal Structure Of Wild Type Egfr In Complex With Tak-788
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.61 Å Release Date: 2022-12-07 Classification: HYDROLASE Ligands: R28 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-12-07
Ligands: R28
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Crystal Structure Of Egfr_D770_N771Insnpg/V948R In Complex With Tak-788
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2022-12-07 Classification: HYDROLASE/HYDROLASE Inhibitor Ligands: R28, EDO, CIT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-12-07
Ligands: R28, EDO, CIT
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Structure Of Egfr_D770_N771Insnpg/V948R In Complex With Covalent Inhibitor Osimertinib.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.10 Å Release Date: 2021-09-22 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: Q6K, EDO, CIT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-09-22
Ligands: Q6K, EDO, CIT
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Crystal Structure Of Anaplastic Lymphoma Kinase (Alk) Bound By Brigatinib
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2018-12-12 Classification: TRANSFERASE Ligands: 6GY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-12-12
Ligands: 6GY
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Crystal Structure Of Choline Kinase Alpha-1 Bound By [4-[(4-Methyl-1,4-Diazepan-1-Yl)Methyl]Phenyl]Methanamine (Compound 11)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2016-01-06 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 5R8 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-01-06
Ligands: 5R8
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Crystal Structure Of Choline Kinase Alpha-1 Bound By 6-[(4-Methyl-1,4-Diazepan-1-Yl)Methyl]Quinoline (Compound 37)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2016-01-06 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 5R9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-01-06
Ligands: 5R9
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Crystal Structure Of Choline Kinase Alpha-1 Bound By 5-[(4-Methyl-1,4-Diazepan-1-Yl)Methyl]-2-[4-[(4-Methyl-1,4-Diazepan-1-Yl)Methyl]Phenyl]Benzenecarbonitrile (Compound 65)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2016-01-06 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 5RA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-01-06
Ligands: 5RA
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Crystal Structure Of Rabbit Ldha In Complex With Ap27460
Organism: Oryctolagus cuniculus
Method: X-RAY DIFFRACTION Resolution:2.23 Å Release Date: 2013-01-23 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: 6P3 |
Organism: Oryctolagus cuniculus
Method: X-RAY DIFFRACTION
Release Date: 2013-01-23
Ligands: 6P3
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Crystal Structure Of Rabbit Ldha In Complex With Ap28669
Organism: Oryctolagus cuniculus
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2013-01-23 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: 1E4 |
Organism: Oryctolagus cuniculus
Method: X-RAY DIFFRACTION
Release Date: 2013-01-23
Ligands: 1E4
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Crystal Structure Of Rabbit Ldha In Complex With Ap28161 And Ap28122
Organism: Oryctolagus cuniculus
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2013-01-23 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: 1E6, 1E5 |
Organism: Oryctolagus cuniculus
Method: X-RAY DIFFRACTION
Release Date: 2013-01-23
Ligands: 1E6, 1E5
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Crystal Structure Of Rabbit Ldha In Complex With A Fragment Inhibitor Ap26256
Organism: Oryctolagus cuniculus
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2013-01-23 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: 1E7 |
Organism: Oryctolagus cuniculus
Method: X-RAY DIFFRACTION
Release Date: 2013-01-23
Ligands: 1E7
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Crystal Structure Of Abl Kinase Domain Bound With A Dfg-Out Inhibitor Ap24534
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2010-12-15 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0LI |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2010-12-15
Ligands: 0LI
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Crystal Structure Of Abl T315I Mutant Kinase Domain Bound With A Dfg-Out Inhibitor Ap24589
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2010-12-15 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: XY3 |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2010-12-15
Ligands: XY3
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Structural Analysis Of Dfg-In And Dfg-Out Dual Src-Abl Inhibitors Sharing A Common Vinyl Purine Template
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2009-12-22 Classification: TRANSFERASE Ligands: B90 |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2009-12-22
Ligands: B90
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Structural Analysis Of Dfg-In And Dfg-Out Dual Src-Abl Inhibitors Sharing A Common Vinyl Purine Template
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.22 Å Release Date: 2009-12-22 Classification: TRANSFERASE Ligands: B91 |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2009-12-22
Ligands: B91
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Ap24534, A Pan-Bcr-Abl Inhibitor For Chronic Myeloid Leukemia, Potently Inhibits The T315I Mutant And Overcomes Mutation-Based Resistance
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2009-11-03 Classification: TRANSFERASE Ligands: 0LI |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2009-11-03
Ligands: 0LI
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Crystal Structure Of Abl Kinase Bound With Ppy-A
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2007-09-18 Classification: TRANSFERASE Ligands: P3Y |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2007-09-18
Ligands: P3Y
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Crystal Structure Of The T315I Mutant Of Abl Kinase Bound With Ppy-A
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2007-09-18 Classification: TRANSFERASE Ligands: P3Y |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2007-09-18
Ligands: P3Y
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Src Kinase In Complex With Inhibitor Ap23451
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2006-10-24 Classification: TRANSFERASE Ligands: 24A |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2006-10-24
Ligands: 24A
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Src Kinase In Complex With Inhibitor Ap23464
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2006-10-24 Classification: TRANSFERASE Ligands: HET |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2006-10-24
Ligands: HET