Search Count: 76
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Structure Of Kras-G12C Bound To 1-[(4Ar,10P,13R)-10-[5-Amino-4-Fluoro-3-Methyl-2-(Trifluoromethyl)Phenyl]-11-Chloro-9-Fluoro-1,2,4A,5-Tetrahydropyrazino[1',2':4,5][1,4]Oxazino[2,3-C]Quinolin-3(4H)-Yl]Prop-2-En-1-One (Compound 15)
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: MG, GDP, A1CII, PEG, GOL, DMS, ACT |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2026-03-11
Ligands: MG, GDP, A1CII, PEG, GOL, DMS, ACT
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Structure Of Kras G12C Bound To Compound 4
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: A1CQ2, GDP, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-03-11
Ligands: A1CQ2, GDP, MG
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Structure Of Kras G12C Bound To Divarasib (Gdc6036)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: GDP, MG, DMS, EDO, A1AWR, PEG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-03-11
Ligands: GDP, MG, DMS, EDO, A1AWR, PEG
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Brg1 Bromodomain In Complex With Vbc Via Compound 17
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.17 Å Release Date: 2024-01-17 Classification: GENE REGULATION Ligands: PO4, GOL, VLH, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-01-17
Ligands: PO4, GOL, VLH, CL
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Vhl/Elongin B/Elongin C Complex With Compound 155
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.19 Å Release Date: 2024-01-17 Classification: LIGASE Ligands: VL6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-01-17
Ligands: VL6
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Brm (Smarca2) Bromodomain In Complex With Ligand 10
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.57 Å Release Date: 2024-01-17 Classification: GENE REGULATION Ligands: ZN, VLC, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-01-17
Ligands: ZN, VLC, CL
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Identification Of Gdc-1971 (Rly-1971), A Shp2 Inhibitor Designed For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2023-10-11 Classification: HYDROLASE Ligands: SO4, YR2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-10-11
Ligands: SO4, YR2
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Identification Of Gdc-1971 (Rly-1971), A Shp2 Inhibitor Designed For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2023-10-11 Classification: HYDROLASE Ligands: SO4, YT2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-10-11
Ligands: SO4, YT2
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Identification Of Gdc-1971 (Rly-1971), A Shp2 Inhibitor Designed For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2023-10-11 Classification: HYDROLASE Ligands: ZH5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-10-11
Ligands: ZH5
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Identification Of Gdc-1971 (Rly-1971), A Shp2 Inhibitor Designed For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2023-10-11 Classification: HYDROLASE/INHIBITOR Ligands: ZJX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-10-11
Ligands: ZJX
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Crystal Structure Of Hcv Ns3/4A D168A Protease In Complex With Jz01-19
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION Resolution:1.89 Å Release Date: 2022-08-31 Classification: HYDROLASE/INHIBITOR Ligands: EDO, ZN, ZJP, SO4 |
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION
Release Date: 2022-08-31
Ligands: EDO, ZN, ZJP, SO4
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Kras G12C In Complex With G-2897
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2022-03-16 Classification: HYDROLASE/Immune System Ligands: Z07, GDP, MG, ACT, CAD, P15, EDO, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: Z07, GDP, MG, ACT, CAD, P15, EDO, DMS
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Crystal Structure Of Hcv Ns3/4A Protease In Complex With Nr01-127
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION Resolution:1.78 Å Release Date: 2022-03-16 Classification: HYDROLASE/INHIBITOR Ligands: ZN, ZJG, EDO, SO4 |
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: ZN, ZJG, EDO, SO4
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Crystal Structure Of Hcv Ns3/4A Protease In Complex With Nr01-115
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION Resolution:1.89 Å Release Date: 2022-03-16 Classification: HYDROLASE/INHIBITOR Ligands: ZN, EDO, ZKA, SO4 |
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: ZN, EDO, ZKA, SO4
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Crystal Structure Of Hcv Ns3/4A Protease In Complex With Nr01-149
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION Resolution:2.11 Å Release Date: 2022-03-16 Classification: HYDROLASE/INHIBITOR Ligands: ZN, ZJJ, EDO, SO4 |
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: ZN, ZJJ, EDO, SO4
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Crystal Structure Of Hcv Ns3/4A Protease In Complex With Nr01-145
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION Resolution:1.65 Å Release Date: 2022-03-16 Classification: HYDROLASE/INHIBITOR Ligands: ZN, ZKJ, EDO, SO4 |
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: ZN, ZKJ, EDO, SO4
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Crystal Structure Of Hcv Ns3/4A D168A Protease In Complex With Nr01-127
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION Resolution:1.99 Å Release Date: 2022-03-16 Classification: HYDROLASE/INHIBITOR Ligands: ZJG, EDO, ZN, SO4 |
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: ZJG, EDO, ZN, SO4
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Crystal Structure Of Hcv Ns3/4A D168A Protease In Complex With Nr01-115
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2022-03-16 Classification: HYDROLASE/INHIBITOR Ligands: ZN, ZKA, EDO, SO4 |
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: ZN, ZKA, EDO, SO4
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Crystal Structure Of Hcv Ns3/4A D168A Protease In Complex With Nr01-149
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION Resolution:1.89 Å Release Date: 2022-03-16 Classification: HYDROLASE/INHIBITOR Ligands: ZN, ZJJ, EDO, SO4 |
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: ZN, ZJJ, EDO, SO4
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Crystal Structure Of Hcv Ns3/4A D168A Protease In Complex With Nr01-145
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2022-03-16 Classification: HYDROLASE/INHIBITOR Ligands: ZKJ, ZN, SO4 |
Organism: Hepacivirus c
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: ZKJ, ZN, SO4