Search Count: 26
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Crystal Structure Of Kirsten Rat Sarcoma G12C Complexed With Gmppnp And Covalently Bound To 1-[(2R,3R)-3-{[(7P)-7-(8-Ethynyl-7-Fluoronaphthalen-1-Yl)-8-Fluoro-2-{ [(2R,4R,7As)-2-Fluorotetrahydro-1H-Pyrrolizin-7A(5H)-Yl]Methoxy}Pyrido[4,3-D] Pyrimidin-4-Yl](Methyl)Amino}-2-Methylpyrrolidin-1-Yl]-3-(Pyrazin-2-Yl)Propan-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.49 Å Release Date: 2026-03-04 Classification: HYDROLASE Ligands: GDP, A1C5K, CA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-03-04
Ligands: GDP, A1C5K, CA
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Crystal Structure Of Kirsten Rat Sarcoma G12C Complexed With Gmppnp And Covalently Bound To An Adduct Of {(2S)-4-[7-(8-Chloronaphthalen-1-Yl)-2-{[(2S)-1-Methylpyrrolidin-2-Yl]Methoxy}-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidin-4-Yl]-1-[(2Z)-2-Fluoro-3-(Pyridin-2-Yl)Prop-2-Enoyl]Piperazin-2-Yl}Acetonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.59 Å Release Date: 2025-11-05 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: GNP, A1B7P, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-11-05
Ligands: GNP, A1B7P, MG
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Crystal Structure Of Kirsten Rat Sarcoma G12C Complexed With Gdp And Covalently Bound To An Adduct Of (2S)-1-{4-[(7P)-7-(8-Ethynyl-7-Fluoro-3-Hydroxynaphthalen-1-Yl)-8-Fluoro-2-{[(2R,4R,7As)-2-Fluorotetrahydro-1H-Pyrrolizin-7A(5H)-Yl]Methoxy}Pyrido[4,3-D]Pyrimidin-4-Yl]Piperazin-1-Yl}-2-Fluoro-3-(1,3-Thiazol-2-Yl)Propan-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2025-11-05 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: GDP, A1B7Q, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-11-05
Ligands: GDP, A1B7Q, MG
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Crystal Structure Of Ap2 Associated Kinase 1 Complexed With 5-[(4-Aminopiperidin-1-Yl)Methyl]-N-{3-[5-(Propan-2-Yl)-1,3,4-Thiadiazol-2-Yl]Phenyl}Pyrrolo[2,1-F][1,2,4]Triazin-4-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2023-07-12 Classification: TRANSFERASE Ligands: YFV, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-07-12
Ligands: YFV, SO4
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Crystal Structure Of Ap2 Associated Kinase 1 Complexed With (5P)-3-({(8R)-5-[(4-Aminopiperidin-1-Yl)Methyl]Pyrrolo[2,1-F][1,2,4]Triazin-4-Yl}Amino)-5-[2-(Propan-2-Yl)-2H-Tetrazol-5-Yl]Phenol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2023-07-12 Classification: TRANSFERASE Ligands: ZRR, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-07-12
Ligands: ZRR, SO4
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Crystal Structure Of Ap2 Associated Kinase 1 Isoform 1 Complexed With Ligand (2R)-2-Amino-N-[3-(Difluorom Ethoxy)-4-(1,3-Oxazol-5-Yl)Phenyl]-4-Methylpentanamide
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.13 Å Release Date: 2022-02-23 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: YFV, SO4, 5OI |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2022-02-23
Ligands: YFV, SO4, 5OI
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Crystal Structure Of Ap2 Associated Kinase 1 Isoform 1 Complexed With Ligand 2-(1-Amino-3-Methylbutyl)-6- (Pyridin-4-Yl)Quinoline-4-Carbonitrile
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.12 Å Release Date: 2022-02-23 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 5P6, SO4 |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2022-02-23
Ligands: 5P6, SO4
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Crystal Structure Of Ap2 Associated Kinase 1 Isoform 1 Complexed With Ligand (2R)-2-Amino-N-[3-(Difluorom Ethoxy)-4-(1,3-Oxazol-5-Yl)Phenyl]-4-Methylpentanamide
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.59 Å Release Date: 2022-02-23 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 5QI, PG6, SO4, YFV |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2022-02-23
Ligands: 5QI, PG6, SO4, YFV
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Crystal Structure Of Ap2 Associated Kinase 1 Isoform 1 Complexed With Ligand N-[3-Methoxy-4-(1,3-Oxazol-5-Yl)Phenyl]-3-(Propan-2-Yl)Piperidine-2-Carboxamide
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2021-07-28 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: YFS, SO4, YFV |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2021-07-28
Ligands: YFS, SO4, YFV
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Crystal Structure Of Ap2 Associated Kinase 1 Isoform 1 Complexed With Ligand (2R)-2-Amino-N-[3-Methoxy-4- (1,3-Oxazol-5-Yl)Phenyl]-4-Methylpentanamide
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2021-07-28 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: YFY, SO4, YFV |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2021-07-28
Ligands: YFY, SO4, YFV
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Human Receptor Protein Tyrosine Phosphatase Gamma, Domain 1, Apo
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2011-12-28 Classification: HYDROLASE Ligands: SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-12-28
Ligands: SO4
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Human Receptor Protein Tyrosine Phosphatase Gamma, Domain 1, In Complex With Vanadate, Orthorhombic Crystal Form
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2011-12-28 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: VO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-12-28
Ligands: VO4
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Human Receptor Protein Tyrosine Phosphatase Gamma, Domain 1, In Complex With Vanadate, Trigonal Crystal Form
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2011-12-28 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: VO4, ACY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-12-28
Ligands: VO4, ACY
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Human Receptor Protein Tyrosine Phosphatase Gamma, Domain 1, In Complex With 3-[(3,4-Dichlorobenzyl)Sulfanyl]Thiophene-2-Carboxylic Acid Via Soaking
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2011-12-28 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: NXY, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-12-28
Ligands: NXY, SO4
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Human Receptor Protein Tyrosine Phosphatase Gamma, Domain 1, In Complex With 3-[(3,4-Dichlorobenzyl)Sulfanyl]Thiophene-2-Carboxylic Acid Via Co-Crystallization
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2011-12-28 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: NXY, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-12-28
Ligands: NXY, SO4
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Human Receptor Protein Tyrosine Phosphatase Gamma, Domain 1, In Complex With 3-[(3-Bromo-4-Chlorobenzyl)Sulfanyl]Thiophene-2-Carboxylic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2011-12-28 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: NX1, ACY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-12-28
Ligands: NX1, ACY
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Human Receptor Protein Tyrosine Phosphatase Gamma, Domain 1, In Complex With 3-[(3,4-Dichlorobenzyl)Sulfanyl]-N-(Methylsulfonyl)Thiophene-2-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2011-12-28 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: NX2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-12-28
Ligands: NX2
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Human Receptor Protein Tyrosine Phosphatase Gamma, Domain 1, In Complex With N-[(3-Aminophenyl)Sulfonyl]-3-[(3,4-Dichlorobenzyl)Sulfanyl]Thiophene-2-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2011-12-28 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: NX3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-12-28
Ligands: NX3
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Human Receptor Protein Tyrosine Phosphatase Gamma, Domain 1, In Complex With 5-[({3-[(3,4-Dichlorobenzyl)Sulfanyl]Thiophen-2-Yl}Carbonyl)Sulfamoyl]-2-Methoxybenzoic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.26 Å Release Date: 2011-12-28 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: NX4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-12-28
Ligands: NX4
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Human Receptor Protein Tyrosine Phosphatase Gamma, Domain 1, In Complex With 2-[(3,4-Dichlorobenzyl)Sulfanyl]Benzoic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2011-12-28 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: NX5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-12-28
Ligands: NX5