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Structure Of Chk1 10-Pt. Mutant Complex With Macrocyclic Lrrk2 Inhibitor Compound 1 ((11R)-8-Chloro-3,11-Dimethyl-2-(Oxan-4-Yl)-2,4,10,11,12,13-Hexahydro-9,5-(Azeno)Pyrazolo[3,4-B][1,4,6,10]Oxatriazacyclotridecine)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.03 Å Release Date: 2026-04-08 Classification: TRANSFERASE/INHIBITOR Ligands: A1C5F |
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Structure Of Chk1 10-Pt. Mutant Complex With Macrocyclic Lrrk2 Inhibitor Compound 7 ((10As,13As)-3-Cyclobutyl-1-Methyl-8-(Trifluoromethyl)-3,4,10A,11,13A,14-Hexahydro-10H,13H-9,5-(Azeno)Furo[3,4-K]Pyrazolo[4,3-B][1,4,6,10]Oxatriazacyclotridecine)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.67 Å Release Date: 2026-04-08 Classification: TRANSFERASE/INHIBITOR Ligands: A1C5G |
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Structure Of Chk1 10-Pt. Mutant Complex With Macrocyclic Lrrk2 Inhibitor Compound 12 ((10As,13As)-3-Cyclopropyl-1-Methyl-8-(Trifluoromethyl)-3,4,10A,11,13A,14-Hexahydro-10H,13H-9,5-(Azeno)Furo[3,4-K]Pyrazolo[4,3-B][1,4,6,10]Oxatriazacyclotridecine)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.74 Å Release Date: 2026-04-08 Classification: TRANSFERASE/INHIBITOR Ligands: A1C5H |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.76 Å Release Date: 2022-08-24 Classification: OXIDOREDUCTASE Ligands: 6IZ |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.69 Å Release Date: 2022-03-16 Classification: OXIDOREDUCTASE Ligands: 6ZI |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.18 Å Release Date: 2022-03-16 Classification: OXIDOREDUCTASE Ligands: 6RI |
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Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:2.04 Å Release Date: 2021-11-03 Classification: PROTEIN BINDING,HYDROLASE Ligands: GOL, 89N |
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Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.27 Å Release Date: 2021-11-03 Classification: PROTEIN BINDING,HYDROLASE Ligands: 89N |
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Organism: Homo sapiens, Bos taurus
Method: X-RAY DIFFRACTION Resolution:2.58 Å Release Date: 2019-12-11 Classification: transferase/transferase inhibitor Ligands: M5V |
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Organism: Homo sapiens, Bos taurus
Method: X-RAY DIFFRACTION Resolution:2.77 Å Release Date: 2019-12-11 Classification: transferase/transferase inhibitor Ligands: M5D |
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Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:3.09 Å Release Date: 2019-05-01 Classification: TRANSFERASE Ligands: K4A |
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Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:3.06 Å Release Date: 2019-05-01 Classification: TRANSFERASE Ligands: K47 |
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The Crystal Structure Of Human Porphobilinogen Deaminase At 2.8A Resolution
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2009-03-03 Classification: TRANSFERASE Ligands: DPM, SO4 |