Search Count: 16
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase In Complex With 2-(4-Fluorophenyl)-N-Methyl-6-[(Methylsulfonyl)Amino]-5-(Propan-2-Yloxy)-1-Benzofuran-3-Carboxamide
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2017-05-10 Classification: TRANSFERASE Ligands: 23E, 2N5, SO4, GOL, PG4 |
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION
Release Date: 2017-05-10
Ligands: 23E, 2N5, SO4, GOL, PG4
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase In Complex With 2-({3-[1-(2-Cyclopropylethyl)-6-Fluoro-4-Hydroxy-2-Oxo-1,2-Dihydroquinolin-3-Yl]-1,1-Dioxo-1,4-Dihydro-1Lambda~6~,2,4-Benzothiadiazin-7-Yl}Oxy)Acetamide
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION Resolution:2.06 Å Release Date: 2017-05-10 Classification: TRANSFERASE Ligands: 23E, 8XV, SO4 |
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION
Release Date: 2017-05-10
Ligands: 23E, 8XV, SO4
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase In Complex With 3-[2-(4-Fluorophenyl)-3-(Methylcarbamoyl)-1-Benzofuran-5-Yl]Benzoic Acid
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION Resolution:2.54 Å Release Date: 2017-05-10 Classification: TRANSFERASE Ligands: 23E, SO4, 8XS, GOL |
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION
Release Date: 2017-05-10
Ligands: 23E, SO4, 8XS, GOL
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase In Complex With 5-[3-(Tert-Butylcarbamoyl)Phenyl]-2-(4-Fluorophenyl)-N-Methyl-1-Benzofuran-3-Carboxamide
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2017-05-10 Classification: TRANSFERASE Ligands: 23E, 8XP, SO4, GOL |
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION
Release Date: 2017-05-10
Ligands: 23E, 8XP, SO4, GOL
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase C316N In Complex With 2-(4-Fluorophenyl)-N-Methyl-5-[3-({2-Methyl-1-Oxo-1-[(1,3,4-Thiadiazol-2-Yl)Amino]Propan-2-Yl}Carbamoyl)Phenyl]-1-Benzofuran-3-Carboxamide
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2017-05-10 Classification: TRANSFERASE Ligands: 23E, 8XM, SO4, GOL |
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION
Release Date: 2017-05-10
Ligands: 23E, 8XM, SO4, GOL
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase In Complex With 4-Fluoro-2-(4-Fluorophenyl)-N-Methyl-5-(2-Methyl-5-{[1-(Pyrimidin-2-Yl)Cyclopropyl]Carbamoyl}Phenyl)-1-Benzofuran-3-Carboxamide (Bms-929075)
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION Resolution:2.95 Å Release Date: 2017-05-10 Classification: TRANSFERASE Ligands: 23E, 8XJ, SO4, GOL |
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION
Release Date: 2017-05-10
Ligands: 23E, 8XJ, SO4, GOL
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna- Dependent Rna Polymerase In Complex With 5-[3-(Tert-Butylcarbamoyl)Phenyl]-6-(Ethylamino)-2-(4-Fluorophenyl)-N-Methylfuro[2,3-B]Pyridine-3-Carboxamide
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION Resolution:3.04 Å Release Date: 2017-03-15 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: 23E, SO4, 7NG |
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION
Release Date: 2017-03-15
Ligands: 23E, SO4, 7NG
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase In Complex With 2-[(Benzenecarbonyl)Amino]-3-[(4-Chlorophenyl)Methoxy]Benzoic Acid
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2016-11-30 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: 23E, 7HL, SO4 |
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION
Release Date: 2016-11-30
Ligands: 23E, 7HL, SO4
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase In Complex With 3-[(4-Chlorophenyl)Methoxy]-2-(1-Oxo-1,3-Dihydro-2H-Isoindol-2-Yl)Benzoic Acid
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2016-11-30 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: 23E, 7HM, SO4 |
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION
Release Date: 2016-11-30
Ligands: 23E, 7HM, SO4
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase In Complex With 2-{[2-(Carboxymethoxy)Benzene-1-Carbonyl]Amino}-3-[(4-Chlorophenyl)Methoxy]Benzoic Acid
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION Resolution:2.57 Å Release Date: 2016-11-30 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: 23E, 7HO, SO4 |
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION
Release Date: 2016-11-30
Ligands: 23E, 7HO, SO4
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna- Dependent Rna Polymerase In Complex With N-{3-[(Benzenecarbonyl)Amino]-4-[(4-Chlorophenyl)Methoxy]Benzene-1-Carbonyl}Glycine
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION Resolution:2.06 Å Release Date: 2016-11-30 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: 23E, 7HH, SO4 |
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION
Release Date: 2016-11-30
Ligands: 23E, 7HH, SO4
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase Complex With (2E)-3-(4-{[(1-{[(13-Cyclohexyl-6-Oxo-6,7-Dihydro-5H-Indolo[1,2-D][1,4]Benzodiazepin-10-Yl)Carbonyl]Amino}Cyclopentyl)Carbonyl]Amino}Phenyl)Prop-2-Enoic Acid
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION Resolution:2.29 Å Release Date: 2011-04-27 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 23E, SO4 |
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION
Release Date: 2011-04-27
Ligands: 23E, SO4
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase Complex With (2E)-3-(4-{[(1-{[(13-Cyclohexyl-6-Oxo-6,7-Dihydro-5H-Indolo[1,2-D][1,4]Benzodiazepin-10-Yl)Carbonyl]Amino}Cyclopentyl)Carbonyl]Amino}Phenyl)Prop-2-Enoic Acid And (2R)-4-(2,6-Dimethoxypyrimidin-4-Yl)-1-[(4-Ethylphenyl)Sulfonyl]-N-(4-Methoxybenzyl)Piperazine-2-Carboxamide
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2011-04-20 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 23E, SO4, 26S |
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION
Release Date: 2011-04-20
Ligands: 23E, SO4, 26S
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase Complex With (2E)-3-(4-{[(1-{[(13-Cyclohexyl-6-Oxo-6,7-Dihydro-5H-Indolo[1,2-D][1,4]Benzodiazepin-10-Yl)Carbonyl]Amino}Cyclopentyl)Carbonyl]Amino}Phenyl)Prop-2-Enoic Acid And (2R)-4-(2,6-Dimethoxypyrimidin-4-Yl)-N-(4-Methoxybenzyl)-1-{[4-(Trifluoromethoxy)Phenyl]Sulfonyl}Piperazine-2-Carboxamide
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2011-04-20 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 23E, SO4, 26F |
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION
Release Date: 2011-04-20
Ligands: 23E, SO4, 26F
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase Complex With (2E)-3-(4-{[(1-{[(13-Cyclohexyl-6-Oxo-6,7-Dihydro-5H-Indolo[1,2-D][1,4]Benzodiazepin-10-Yl)Carbonyl]Amino}Cyclopentyl)Carbonyl]Amino}Phenyl)Prop-2-Enoic Acid And (2R)-4-(6-Chloropyridazin-3-Yl)-N-(4-Methoxybenzyl)-1-{[4-(Trifluoromethoxy)Phenyl]Sulfonyl}Piperazine-2-Carboxamide
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2011-04-20 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 23E, 46F, SO4 |
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION
Release Date: 2011-04-20
Ligands: 23E, 46F, SO4
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase Complex With (2E)-3-(4-{[(1-{[(13-Cyclohexyl-6-Oxo-6,7-Dihydro-5H-Indolo[1,2-D][1,4]Benzodiazepin-10-Yl)Carbonyl]Amino}Cyclopentyl)Carbonyl]Amino}Phenyl)Prop-2-Enoic Acid And N-Cyclopropyl-6-[(3R)-3-{[4-(Trifluoromethoxy)Benzyl]Carbamoyl}-4-{[4-(Trifluoromethoxy)Phenyl]Sulfonyl}Piperazin-1-Yl]Pyridazine-3-Carboxamide
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION Resolution:3.22 Å Release Date: 2011-04-20 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 23E, 63F, SO4 |
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION
Release Date: 2011-04-20
Ligands: 23E, 63F, SO4