ISDA: 9ZY5

Deposition Date 2026-01-05

Release Date 2026-10-07

Last Version Date 2026-10-07

Entry Detail

PDB ID:

9ZY5

Keywords:

MEMBRANE PROTEIN

Title:

Ca2+ bound gated state Connexin-46

Biological Source:

Source Organism(s):

Ovis aries (Taxon ID: 9940)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.60 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Gap junction alpha-3 protein
Gene (Uniprot):GJA3
Chain IDs:A, B, C, D, E, F, G, H, I, J, K, L
Chain Length:413
Number of Molecules:12
Biological Source:Ovis aries

UniProt ID:Q9TU17 Pfam ID:PF00029

Ligand Molecules

MC3

Primary Citation

Calcium induced N-terminal gating and pore collapse in connexin-46/50 gap junctions

Flores, J.A, O'Neill, S.E, Jarodsky, J.M, Haddad, B.G, Reichow, S.L.Show

Nat Commun ? ? ? (2026)

DOI: 10.1038/s41467-026-77891-5

Primary Citation of related structures

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