9ZX7 image
Deposition Date 2026-01-03
Release Date 2026-09-23
Last Version Date 2026-09-23
Entry Detail
PDB ID:
9ZX7
Keywords:
TRANSFERASE
Title:
Crystal structure of the N4BP2 polynucleotide kinase domain complexed with ATP or ADP, Mg, and the trideoxynucleotide substrate dACA or its 5'-phosphorylated product dpACA.
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.21 Å
R-Value Free:
0.23
R-Value Work:
0.19
R-Value Observed:
0.19
Space Group:
I 2 2 2
9ZX7 validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:NEDD4-binding protein 2
Gene (Uniprot):N4BP2
Chain IDs:A, B, C
Chain Length:0
Number of Molecules:3
Biological Source:Homo sapiens
UniProt ID:Q86UW6 Pfam ID:PF13671 EC:3.-.-.-
Polymer Type:polydeoxyribonucleotide
Molecule:5'-OH DNA (5'-d(ApCpA)-3') or
Chain IDs:D, E, F
Chain Length:0
Number of Molecules:3
Biological Source:synthetic construct
Ligand Molecules
ADP
ATP
EDO
MG
SO4
Primary Citation
Structure, Specificity, and Catalytic Mechanism of the Polynucleotide Kinase Domains from the Human N4BP2 Kinase Family
Nat Commun ? ? ? (2026)
Primary Citation of related structures
9ZX7
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