ISDA: 9ZTC

Deposition Date 2025-12-23

Release Date 2026-04-22

Last Version Date 2026-04-22

Entry Detail

PDB ID:

9ZTC

Keywords:

MEMBRANE PROTEIN

Title:

Beta-1,3-glucan synthase Fks1 S643P from Saccharomyces Cerevisiae

Biological Source:

Source Organism(s):

Saccharomyces cerevisiae (Taxon ID: 4932)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.50 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:1,3-beta-glucan synthase comp
Gene (Uniprot):FKS1
Mutagens:S643P
Chain IDs:A
Chain Length:1931
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P38631 Pfam ID:PF14288, PF23605, PF02364

Ligand Molecules

Y01

Primary Citation

Structural basis of fungal beta-1,3-glucan synthase inhibition by caspofungin

Ren, Z, Chhetri, A, Liu, C, Offner, S.Y, Sharma, K, Borgnia, M.J, Im, W, Yokoyama, K, Lee, S.-Y.Show

Nature ? ? ? (2026)

DOI: 10.1038/s41586-026-10409-7

Primary Citation of related structures

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