9ZOE image
Deposition Date 2025-12-15
Release Date 2026-09-30
Last Version Date 2026-09-30
Entry Detail
PDB ID:
9ZOE
Title:
Structure of RyR1 in complex with rosuvastatin (Ca2+/CFF/ATP dataset; open pore)
Biological Source:
Source Organism(s):
Method Details:
Experimental Method:
Resolution:
2.90 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Ryanodine receptor 1
Gene (Uniprot):RYR1
Chain IDs:B (auth: A), F (auth: B), G (auth: D), H (auth: C)
Chain Length:0
Number of Molecules:4
Biological Source:Oryctolagus cuniculus
Polymer Type:polypeptide(L)
Molecule:Peptidyl-prolyl cis-trans iso
Gene (Uniprot):FKBP1A
Chain IDs:A (auth: E), C (auth: F), D (auth: G), E (auth: H)
Chain Length:0
Number of Molecules:4
Biological Source:Oryctolagus cuniculus
Primary Citation
Structural basis for rosuvastatin-induced activation of skeletal muscle ryanodine receptor 1
Nat Commun ? ? ? (2026)
DOI: 10.1038/s41467-026-77372-9
Primary Citation of related structures
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