9ZO8 image
Deposition Date 2025-12-15
Release Date 2026-09-30
Last Version Date 2026-09-30
Entry Detail
PDB ID:
9ZO8
Keywords:
TRANSPORT PROTEIN
Title:
Structure of RyR1 in presence of rosuvastatin (including auxiliary transmembrane helices TMx1 and TMx2; Ca2+/CFF/ATP dataset; closed pore)
Biological Source:
Source Organism(s):
Oryctolagus cuniculus (Taxon ID: 9986)
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.70 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9ZO8 validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Ryanodine receptor 1
Gene (Uniprot):RYR1
Chain IDs:B (auth: A), C (auth: B), D, E (auth: C)
Chain Length:0
Number of Molecules:4
Biological Source:Oryctolagus cuniculus
UniProt ID:P11716 Pfam ID:PF08709, PF02815, PF01365, PF00622, PF02026, PF21119, PF08454, PF06459, PF00520
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Peptidyl-prolyl cis-trans iso
Gene (Uniprot):FKBP1A
Chain IDs:A (auth: E), F, G, H
Chain Length:0
Number of Molecules:4
Biological Source:Oryctolagus cuniculus
UniProt ID:P62943 Pfam ID:PF00254 EC:5.2.1.8
Ligand Molecules
ATP
CA
CFF
PCW
ZN
Primary Citation
Structural basis for rosuvastatin-induced activation of skeletal muscle ryanodine receptor 1
Nat Commun ? ? ? (2026)
DOI: 10.1038/s41467-026-77372-9
Primary Citation of related structures
9ZO8
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