ISDA: 9ZLW

Deposition Date 2025-12-09

Release Date 2026-10-21

Last Version Date 2026-10-21

Entry Detail

PDB ID:

9ZLW

Keywords:

TRANSPORT PROTEIN

Title:

Human Mfsd2b bound to S1P in outward-facing conformation, digitonin extraction

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.08 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Sphingosine-1-phosphate trans
Gene (Uniprot):MFSD2B
Chain IDs:A
Chain Length:443
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:A0A2I3JL00

Ligand Molecules

S1P

Primary Citation

Structure and mechanism of human sphingosine-1-phosphate transporter MFSD2B.

Ahmed, S, Huang, M, Dai, Y, Yang, X, Dong, J, Yu, X, Lee, C.H, Nguyen, L.N.Show

Nat Commun 17 ? ? (2026)

PMID: 42717192 DOI: 10.1038/s41467-026-76690-2

Primary Citation of related structures

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