ISDA: 9ZHH

Deposition Date 2025-12-03

Release Date 2026-07-29

Last Version Date 2026-07-29

Entry Detail

PDB ID:

9ZHH

Keywords:

CELL ADHESION

Title:

Cryo-EM structure of IGFBP7 dodecamer. The 3D refinement was focused on the central part of the dodecamer, which contains 12 IgC2 domains.

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.40 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Insulin-like growth factor-bi
Gene (Uniprot):IGFBP7
Chain IDs:A, B (auth: G), C (auth: B), D (auth: H), E (auth: C), F (auth: I), G (auth: D), H (auth: J), I (auth: E), J (auth: K), K (auth: F), L
Chain Length:282
Number of Molecules:12
Biological Source:Homo sapiens

UniProt ID:Q16270 Pfam ID:PF00219, PF07648, PF07679

Ligand Molecules

Primary Citation

IGFBP7 is a soluble cell adhesion molecule

Cai, K, Zhang, X.W, Bai, X.C.Show

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Primary Citation of related structures

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