9ZGA image
Deposition Date 2025-12-02
Release Date 2026-07-08
Last Version Date 2026-07-08
Entry Detail
PDB ID:
9ZGA
Keywords:
VIRAL PROTEIN/IMMUNE SYSTEM
Title:
Crystal structure of DH511.12P Fab in complex with HIV-1 gp41 MPER peptide and phosphatidic acid (06:0 PA); double-lipid form
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Human immunodeficiency virus 1 (Taxon ID: 11676)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.97 Å
R-Value Free:
0.26
R-Value Work:
0.22
R-Value Observed:
0.22
Space Group:
P 31 2 1
9ZGA validation report missing
Macromolecular Entities
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Antibody DH511.12P Fab heavy
Chain IDs:A
Chain Length:236
Number of Molecules:1
Biological Source:Homo sapiens
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Antibody DH511.12P Fab light
Chain IDs:B
Chain Length:217
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Transmembrane protein gp41
Gene (Uniprot):env
Chain IDs:C
Chain Length:19
Number of Molecules:1
Biological Source:Human immunodeficiency virus 1
UniProt ID:Q73372
Ligand Molecules
44E
PEG
PO4
Primary Citation
Structural basis of membrane engagement and polyreactivity control in HIV-1 MPER broadly neutralizing antibodies
To Be Published ? ? ? (?)
Primary Citation of related structures
9ZGA
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