9ZEB image
Deposition Date 2025-11-28
Release Date 2026-09-30
Last Version Date 2026-09-30
Entry Detail
PDB ID:
9ZEB
Title:
Cryo-EM structure of the TREX-2.1 complex (Thp3/Csn12/Sem1) bound to the DEAD-box ATPase Sub2
Biological Source:
Source Organism(s):
Expression System(s):
Method Details:
Experimental Method:
Resolution:
3.72 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Protein THP3
Gene (Uniprot):THP3
Chain IDs:A
Chain Length:0
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
Polymer Type:polypeptide(L)
Molecule:Cop9 signalosome complex subu
Gene (Uniprot):CSN12
Chain IDs:B
Chain Length:0
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
Polymer Type:polypeptide(L)
Molecule:26S proteasome complex subuni
Gene (Uniprot):SEM1
Chain IDs:C
Chain Length:0
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
Polymer Type:polypeptide(L)
Molecule:ATP-dependent RNA helicase SU
Gene (Uniprot):SUB2
Chain IDs:D
Chain Length:0
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
Ligand Molecules
Primary Citation
Conserved mRNP remodeling mechanism of the TREX-2.1 complex.
Nucleic Acids Res. 54 ? ? (2026)
PMID: 42728799 DOI: 10.1093/nar/gkag884
Primary Citation of related structures
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