ISDA: 9ZDY

Deposition Date 2025-11-26

Release Date 2026-09-16

Last Version Date 2026-09-16

Entry Detail

PDB ID:

9ZDY

Keywords:

TRANSPORT PROTEIN

Title:

Human TTR-C10A at pH 4

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.90 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Transthyretin
Gene (Uniprot):TTR
Chain IDs:A, B, C, D
Chain Length:0
Number of Molecules:4
Biological Source:Homo sapiens

UniProt ID:P02766 Pfam ID:PF00576

Ligand Molecules

Primary Citation

Transthyretin can denature by an alternative pathway.

Jager, M, Schafer, J.H, Lander, G.C, Powers, E.T, Gruebele, M, Kelly, J.W.Show

Proc.Natl.Acad.Sci.USA 123 e2536532123 e2536532123 (2026)

PMID: 42709794 DOI: 10.1073/pnas.2536532123

Primary Citation of related structures

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