ISDA: 9ZBY

Deposition Date 2025-11-21

Release Date 2026-08-26

Last Version Date 2026-08-26

Entry Detail

PDB ID:

9ZBY

Keywords:

VIRAL PROTEIN/IMMUNE SYSTEM

Title:

Crystal structure of SARS-CoV-2 Omicron BA.1 receptor binding domain in complex with antibodies HB148-M4 and LY-CoV1404

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Severe acute respiratory syndrome coronavirus 2 (Taxon ID: 2697049)

Expression System(s):

Cricetulus griseus, Spodoptera frugiperda

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.73 Å

R-Value Free:

0.25

R-Value Work:

0.20

R-Value Observed:

0.20

Space Group:

C 1 2 1

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Antibody LY-CoV1404 Fab Heavy
Chain IDs:C (auth: A)
Chain Length:222
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Antibody LY-CoV1404 Fab Light
Chain IDs:D (auth: B)
Chain Length:215
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Spike protein S1
Chain IDs:E (auth: C)
Chain Length:205
Number of Molecules:1
Biological Source:Severe acute respiratory syndrome coronavirus 2

Polymer Type:polypeptide(L)
Molecule:Antibody HB148-M4 Fab Heavy C
Chain IDs:A (auth: H)
Chain Length:221
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Antibody HB148-M4 Fab Light C
Chain IDs:B (auth: L)
Chain Length:217
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules