9ZBW image
Deposition Date 2025-11-21
Release Date 2026-08-26
Last Version Date 2026-08-26
Entry Detail
PDB ID:
9ZBW
Title:
Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies HB148 and LY-CoV1404
Biological Source:
Expression System(s):
Method Details:
Experimental Method:
Resolution:
3.10 Å
R-Value Free:
0.25
R-Value Work:
0.21
R-Value Observed:
0.21
Space Group:
P 1
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Antibody LY-CoV1404 Fab Heavy
Chain IDs:A, F (auth: E)
Chain Length:222
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Antibody LY-CoV1404 Fab Light
Chain IDs:B, G (auth: F)
Chain Length:215
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Spike protein S1
Chain IDs:D (auth: C), I
Chain Length:205
Number of Molecules:2
Biological Source:Severe acute respiratory syndrome coronavirus 2
Polymer Type:polypeptide(L)
Molecule:Antibody HB148 Fab Heavy Chai
Chain IDs:C (auth: H), H (auth: G)
Chain Length:221
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Antibody HB148 Fab Light Chai
Chain IDs:E (auth: L), J
Chain Length:217
Number of Molecules:2
Biological Source:Homo sapiens
Primary Citation
Somatic Evolution of a Germline Antibody Expands its Breadth to Neutralize Early SARS-CoV-2 Omicron Variants.
Adv Sci ? e76522 e76522 (2026)
PMID: 42439327 DOI: 10.1002/advs.76522
Primary Citation of related structures
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