ISDA: 9ZBC

Deposition Date 2025-11-20

Release Date 2026-09-09

Last Version Date 2026-09-09

Entry Detail

PDB ID:

9ZBC

Keywords:

TRANSFERASE/INHIBITOR

Title:

Human GGPPS in the Open Hexamer Conformation

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.25 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Geranylgeranyl pyrophosphate
Gene (Uniprot):GGPS1
Chain IDs:A, B, C, D (auth: E), E (auth: F), F (auth: G)
Chain Length:301
Number of Molecules:6
Biological Source:Homo sapiens

UniProt ID:O95749 Pfam ID:PF00348 EC:2.5.1.29

Primary Citation

Human GGPPS in the Open Hexamer Conformation

Ferens, F.G, Tsantrizos, Y.S, Lemieux, M.J.Show

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Primary Citation of related structures

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