ISDA: 9Z8I

Deposition Date 2025-11-18

Release Date 2026-08-19

Last Version Date 2026-09-02

Entry Detail

PDB ID:

9Z8I

Keywords:

STRUCTURAL PROTEIN

Title:

Ligand-free solution (NMR) structure of the Mena EVH1 domain

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

SOLUTION NMR

Conformers Calculated:

Conformers Submitted:

Selection Criteria:

all calculated structures submitted

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Protein enabled homolog
Gene (Uniprot):ENAH
Chain IDs:A
Chain Length:115
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q8N8S7 Pfam ID:PF00568

Ligand Molecules

Primary Citation

Mena EVH1 Interacts with PTP1B Via a Distributed Interface Without Regulating Enzymatic Activity.

LaComb, L, Cahill, S.M, Bonanno, J.B, Cowburn, D, Almo, S.C, Ghosh, A.Show

Biochemistry 65 2470 2484 (2026)

PMID: 42610746 DOI: 10.1021/acs.biochem.6c00299

Primary Citation of related structures

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