ISDA: 9Z7Q

Deposition Date 2025-11-17

Release Date 2026-07-15

Last Version Date 2026-07-15

Entry Detail

PDB ID:

9Z7Q

Keywords:

IMMUNE SYSTEM/RNA

Title:

Cryo-EM Structure of the Type III-Bv CRISPR Complex from Dissulfurispira thermophila bound to a crRNA

Biological Source:

Source Organism(s):

Dissulfurispira thermophila (Taxon ID: 2715679)
Escherichia phage MS2 (Taxon ID: 12022)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.00 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Type III-B CRISPR-associated
Gene (Uniprot):JZK55_14980
Chain IDs:A
Chain Length:612
Number of Molecules:1
Biological Source:Dissulfurispira thermophila

UniProt ID:A0A7G1H3Q2 Pfam ID:PF12469, PF22335

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Type III-B CRISPR module-asso
Gene (Uniprot):JZK55_14970
Chain IDs:B
Chain Length:360
Number of Molecules:1
Biological Source:Dissulfurispira thermophila

UniProt ID:A0A7G1H1A4 Pfam ID:PF09700

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Type III-B CRISPR module RAMP
Gene (Uniprot):JZK55_14950
Chain IDs:C, D, E
Chain Length:315
Number of Molecules:3
Biological Source:Dissulfurispira thermophila

UniProt ID:A0A7G1H376 Pfam ID:PF03787

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:CRISPR type III-B/RAMP module
Gene (Uniprot):JZK55_14940
Chain IDs:F, G
Chain Length:140
Number of Molecules:2
Biological Source:Dissulfurispira thermophila

UniProt ID:A0A7G1H353 Pfam ID:PF09701

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:CSD domain-containing protein
Gene (Uniprot):JZK55_14930
Chain IDs:H
Chain Length:376
Number of Molecules:1
Biological Source:Dissulfurispira thermophila

UniProt ID:A0A7G1H339 Pfam ID:PF00313, PF03787

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Cmr1-MntA
Chain IDs:J (auth: I)
Chain Length:438
Number of Molecules:1
Biological Source:Dissulfurispira thermophila

UniProt ID:A0A7G1H1S1 Pfam ID:PF03787, PF18765

Polymer Type:polyribonucleotide
Molecule:RNA (38-MER)
Chain IDs:I (auth: N)
Chain Length:38
Number of Molecules:1
Biological Source:Escherichia phage MS2

Ligand Molecules

Primary Citation

Identification and structure determination of a type III-Bv CRISPR complex that post-translationally modifies an associated toxin.

Pandey, S, Burman, N, Henriques, W.S, Wiegand, T, Zahl, T, Nyquist, H, Spreeuw, T, Buyukyoruk, M, Wiedenheft, B.Show

Structure ? ? ? (2026)

PMID: 42385699 DOI: 10.1016/j.str.2026.06.002

Primary Citation of related structures

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