ISDA: 9Z6Z

Deposition Date 2025-11-14

Release Date 2026-04-29

Last Version Date 2026-04-29

Entry Detail

PDB ID:

9Z6Z

Keywords:

IMMUNE SYSTEM

Title:

Structure of the resting EcDRT3 reverse transcriptase in complex with its non-coding RNA

Biological Source:

Source Organism(s):

Escherichia coli (Taxon ID: 562)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.60 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Drt3a reverse transcriptase p
Chain IDs:A, B, C, D, E, F
Chain Length:426
Number of Molecules:6
Biological Source:Escherichia coli

UniProt ID:9Z6Z

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Drt3b reverse transcriptase p
Chain IDs:G (auth: H), H (auth: I), I (auth: J), J (auth: K), K (auth: L), L (auth: M)
Chain Length:650
Number of Molecules:6
Biological Source:Escherichia coli

UniProt ID:9Z6Z

Polymer Type:polyribonucleotide
Molecule:non-coding RNA
Chain IDs:M (auth: R), N (auth: S), O (auth: T), P (auth: U), Q (auth: V), R (auth: W)
Chain Length:138
Number of Molecules:6
Biological Source:Escherichia coli

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(P*TP*GP*TP*GP*T)-3'
Chain IDs:S (auth: X), U (auth: Z), W (auth: b), Y (auth: d), AA (auth: f), CA (auth: h)
Chain Length:426
Number of Molecules:6
Biological Source:Escherichia coli

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(P*AP*CP*AP*CP*AP*CP
Chain IDs:T (auth: Y), V (auth: a), X (auth: c), Z (auth: e), BA (auth: g), DA (auth: i)
Chain Length:426
Number of Molecules:6
Biological Source:Escherichia coli

Ligand Molecules

Primary Citation

Protein-templated synthesis of dinucleotide repeat DNA by an antiphage reverse transcriptase.

Deng, P, Lee, H, Armijo, C, Wang, H, Gao, A.Show

Science ? eaed1656 eaed1656 (2026)

PMID: 41990131 DOI: 10.1126/science.aed1656

Primary Citation of related structures

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