ISDA: 9Z5U

Deposition Date 2025-11-12

Release Date 2026-07-01

Last Version Date 2026-07-01

Entry Detail

PDB ID:

9Z5U

Keywords:

VIRAL PROTEIN

Title:

Cryo-EM structure of a soluble HCV E1E2 antigen in complex with AT1211 fab

Biological Source:

Source Organism(s):

Hepacivirus hominis (Taxon ID: 3052230)
Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.06 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Protein Blast

Polymer Type:polypeptide(L)
Molecule:sE1E2
Chain IDs:A
Chain Length:589
Number of Molecules:1
Biological Source:Hepacivirus hominis

Protein Blast

Polymer Type:polypeptide(L)
Molecule:AT1211 Heavy Chain
Chain IDs:B (auth: H)
Chain Length:229
Number of Molecules:1
Biological Source:Homo sapiens

Protein Blast

Polymer Type:polypeptide(L)
Molecule:AT1211 Light Chain
Chain IDs:C (auth: L)
Chain Length:214
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

NAG

Primary Citation

Structure-based design of stable recombinant hepatitis C virus E1E2 heterodimers

Capella-Pujol, J, Mulder, F.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

Feedback Form