9Z3T image
Deposition Date 2025-11-07
Release Date 2026-09-02
Last Version Date 2026-09-02
Entry Detail
PDB ID:
9Z3T
Keywords:
SIGNALING PROTEIN
Title:
Crystal structure of the activin B:follistatin 288 complex
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.72 Å
R-Value Free:
0.27
R-Value Work:
0.22
R-Value Observed:
0.23
Space Group:
C 1 2 1
9Z3T validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Inhibin beta B chain
Gene (Uniprot):INHBB
Chain IDs:A, B
Chain Length:115
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P09529 Pfam ID:PF00019
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Follistatin
Gene (Uniprot):FST
Chain IDs:C, D
Chain Length:288
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P19883 Pfam ID:PF21333, PF09289, PF07648
Ligand Molecules
EDO
SO4
Primary Citation
The crystal structure of the activin B:Fst288 complex and computational insights into the broad antagonistic activity and specificity of follistatin.
J.Biol.Chem. ? 113459 113459 (2026)
PMID: 42607890 DOI: 10.1016/j.jbc.2026.113459
Primary Citation of related structures
9Z3T
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