ISDA: 9Z0V

Deposition Date 2025-11-03

Release Date 2026-10-14

Last Version Date 2026-10-21

Entry Detail

PDB ID:

9Z0V

Keywords:

IMMUNE SYSTEM

Title:

Fab structure of anti-tau monoclonal antibody 9E

Biological Source:

Source Organism(s):

Mus musculus (Taxon ID: 10090)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.83 Å

R-Value Free:

0.22

R-Value Work:

0.18

R-Value Observed:

0.18

Space Group:

I 41 2 2

Download Validation Report

Macromolecular Entities

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Heavy chain of Fab fragment o
Chain IDs:B (auth: H)
Chain Length:236
Number of Molecules:1
Biological Source:Mus musculus

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Light chain of Fab fragment o
Chain IDs:A (auth: L)
Chain Length:219
Number of Molecules:1
Biological Source:Mus musculus

Ligand Molecules

PO4

Primary Citation

Tau pSer396 and pSer404 Define Distinct Epitope Regions Linked to Different Antibody Functions.

Pan, R, Congdon, E.E, Chukwu, J.E, Luo, C.C, Sigurdsson, E.M, Kong, X.P.Show

Biorxiv ? ? ? (2026)

PMID: 42079100 DOI: 10.64898/2026.04.16.716390

Primary Citation of related structures

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