9YSM image
Deposition Date 2025-10-19
Release Date 2026-06-10
Last Version Date 2026-06-10
Entry Detail
PDB ID:
9YSM
Keywords:
HYDROLASE
Title:
Human DCTPP1 bound to MPD
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.81 Å
R-Value Free:
0.22
R-Value Work:
0.18
R-Value Observed:
0.18
Space Group:
P 1 2 1
9YSM validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:dCTP pyrophosphatase 1
Gene (Uniprot):DCTPP1
Chain IDs:A, B, C, D
Chain Length:110
Number of Molecules:4
Biological Source:Homo sapiens
UniProt ID:Q9H773 Pfam ID:PF12643 EC:3.6.1.12
Ligand Molecules
MG
MPD
Primary Citation
Structural insights into novel DCTPP1 antagonists and their synergistic action with DNMT inhibitors
To Be Published ? ? ? (?)
Primary Citation of related structures
9YSM
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