ISDA: 9YQK

Deposition Date 2025-10-15

Release Date 2026-08-12

Last Version Date 2026-08-12

Entry Detail

PDB ID:

9YQK

Keywords:

PROTEIN BINDING

Title:

C-terminal LRRK2 bound to C12 DARPin

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Spodoptera frugiperda, Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.60 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Leucine-rich repeat serine/th
Chain IDs:A
Chain Length:2527
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:C12 DARPin
Chain IDs:B
Chain Length:131
Number of Molecules:1
Biological Source:synthetic construct

Ligand Molecules

Primary Citation

LRRK2 bound to C12 DARPin

Sanz-Murillo, M, Leschziner, A.Show

Cell(Cambridge,Mass.) ? ? ? (2026)

DOI: 10.1016/j.cell.2026.07.027

Primary Citation of related structures

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