9YOB image
Deposition Date 2025-10-13
Release Date 2026-10-21
Last Version Date 2026-10-21
Entry Detail
PDB ID:
9YOB
Keywords:
Title:
Crystal structure of integrin a4b1 headpiece in complex with Bio-1211 (Mg)
Biological Source:
Source Organism(s):
Expression System(s):
Method Details:
Experimental Method:
Resolution:
3.00 Å
R-Value Free:
0.29
R-Value Work:
0.24
R-Value Observed:
0.25
Space Group:
P 21 21 21
Macromolecular Entities
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Integrin alpha-4,Integrin alp
Gene (Uniprot):ITGAV, ITGA4
Chain IDs:A
Chain Length:597
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Integrin beta-1
Gene (Uniprot):ITGB1
Chain IDs:B
Chain Length:490
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Bio-1211
Chain IDs:C (auth: I)
Chain Length:5
Number of Molecules:1
Biological Source:synthetic construct
Primary Citation
Conformational landscape of integrin a4b1 and its recognition of VCAM and conformation-stabilizing small molecules
To Be Published ? ? ? (?)
Primary Citation of related structures
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