ISDA: 9YMC

Deposition Date 2025-10-09

Release Date 2026-06-03

Last Version Date 2026-06-03

Entry Detail

PDB ID:

9YMC

Keywords:

RNA BINDING PROTEIN/RNA

Title:

Structure of AGO2 passenger-ejecting RISC (ej-RISC)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Trichoplusia ni

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.28 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Protein argonaute-2
Gene (Uniprot):AGO2
Chain IDs:B (auth: A)
Chain Length:864
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q9UKV8 Pfam ID:PF16486, PF08699, PF02170, PF16488, PF16487, PF02171 EC:3.1.26.-

Polymer Type:polyribonucleotide
Molecule:RNA (5'-R(P*UP*AP*AP*AP*GP*UP
Chain IDs:C (auth: B)
Chain Length:23
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polyribonucleotide
Molecule:RNA (5'-R(P*GP*CP*AP*CP*UP*UP
Chain IDs:A (auth: C)
Chain Length:28
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

Primary Citation

Structure of AGO2 passenger-ejecting RISC (ej-RISC)

Zhang, H, Adhav, V.A, Kehling, A.C, Nakanishi, K.Show

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Primary Citation of related structures

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