9YLE image
Deposition Date 2025-10-08
Release Date 2026-06-03
Last Version Date 2026-06-03
Entry Detail
PDB ID:
9YLE
Keywords:
TRANSCRIPTION/DNA
Title:
State 3 MLL4FC bound to a nucleosome premodified with H2BK120ub and H4K16ac
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)
Expression System(s):
Escherichia coli, Spodoptera frugiperda
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.63 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9YLE validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Histone H3.1
Gene (Uniprot):H3C1, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3C10, H3C11, H3C12
Chain IDs:E (auth: A), I (auth: E)
Chain Length:135
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P68431 Pfam ID:PF00125
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Histone H4
Gene (Uniprot):H4C1, H4C2, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9, H4C11, H4C12, H4C13, H4C14, H4C15, H4C16
Chain IDs:F (auth: B), J (auth: F)
Chain Length:102
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P62805 Pfam ID:PF15511
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Histone H2A type 1-B/E
Gene (Uniprot):H2AC4, H2AC8
Chain IDs:G (auth: C), K (auth: G)
Chain Length:129
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P04908 Pfam ID:PF00125, PF16211
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Histone H2B type 2-E
Gene (Uniprot):H2BC21
Chain IDs:H (auth: D), L (auth: H)
Chain Length:125
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:Q16778 Pfam ID:PF00125
Polymer Type:polydeoxyribonucleotide
Molecule:DNA (145-MER)
Chain IDs:O (auth: I)
Chain Length:147
Number of Molecules:1
Biological Source:synthetic construct
Polymer Type:polydeoxyribonucleotide
Molecule:DNA (145-MER)
Chain IDs:M (auth: J)
Chain Length:147
Number of Molecules:1
Biological Source:synthetic construct
Protein Blast
Polymer Type:polypeptide(L)
Molecule:[histone H3]-lysine(4) N-meth
Gene (Uniprot):KMT2D, KMT2D
Chain IDs:B (auth: K)
Chain Length:1256
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:A0A6P6IDI8,O14686 Pfam ID:PF13832, PF05964, PF05965, PF00856 EC:2.1.1.364
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Retinoblastoma-binding protei
Gene (Uniprot):RBBP5
Chain IDs:C (auth: N)
Chain Length:538
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q15291 Pfam ID:PF00400
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Ubiquitin
Gene (Uniprot):UBB
Chain IDs:A (auth: O)
Chain Length:76
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P0CG47 Pfam ID:PF00240
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Protein dpy-30 homolog
Gene (Uniprot):DPY30
Chain IDs:P, Q
Chain Length:99
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:Q9C005 Pfam ID:PF05186
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:WD repeat-containing protein
Gene (Uniprot):WDR5
Chain IDs:N (auth: R)
Chain Length:334
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P61964 Pfam ID:PF25175
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Set1/Ash2 histone methyltrans
Gene (Uniprot):ASH2L
Chain IDs:D (auth: T)
Chain Length:628
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9UBL3 Pfam ID:PF21257, PF21198, PF00622
Primary Citation
State 3 MLL4FC bound to a nucleosome premodified with H2BK120ub and H4K16ac
To Be Published ? ? ? (?)
Primary Citation of related structures
9YLE
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