ISDA: 9YJ2

Deposition Date 2025-10-03

Release Date 2026-10-07

Last Version Date 2026-10-07

Entry Detail

PDB ID:

9YJ2

Keywords:

VIRAL PROTEIN/IMMUNE SYSTEM

Title:

PC94-A.30 Fab in complex with BG505 SOSIP trimer and RM20A3 Fab

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Macaca mulatta (Taxon ID: 9544)
Human immunodeficiency virus 1 (Taxon ID: 11676)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.10 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:BG505 SOSIP gp120
Chain IDs:E (auth: A), K (auth: C), Q (auth: E)
Chain Length:516
Number of Molecules:3
Biological Source:Human immunodeficiency virus 1

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:BG505 SOSIP gp41
Chain IDs:F (auth: B), L (auth: D), R (auth: F)
Chain Length:153
Number of Molecules:3
Biological Source:Human immunodeficiency virus 1

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:PC94-A.30 Fab heavy chain
Chain IDs:A (auth: H), G (auth: J), M (auth: P)
Chain Length:233
Number of Molecules:3
Biological Source:Homo sapiens

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:RM20A3 Fab heavy chain
Chain IDs:B (auth: I), H (auth: K), N (auth: Q)
Chain Length:229
Number of Molecules:3
Biological Source:Macaca mulatta

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:PC94-A.30 light chain
Chain IDs:C (auth: L), I (auth: N), O (auth: R)
Chain Length:214
Number of Molecules:3
Biological Source:Homo sapiens

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:RM20A3 light chain
Chain IDs:D (auth: M), J (auth: O), P (auth: S)
Chain Length:215
Number of Molecules:3
Biological Source:Macaca mulatta

Ligand Molecules

NAG

Primary Citation

Tolerance of multiple glycan conformations by an N332-directed HIV bnAb lineage provides a roadmap to broad neutralization

Nemoz, B, Rouzeau, R.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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