ISDA: 9YGI

Deposition Date 2025-09-29

Release Date 2026-07-29

Last Version Date 2026-07-29

Entry Detail

PDB ID:

9YGI

Keywords:

IMMUNE SYSTEM

Title:

Cryo-EM structure of L9-21 in complex with Plasmodium falciparum circumsporozoite protein (PfCSP)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Plasmodium falciparum (isolate 3D7) (Taxon ID: 36329)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.98 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Circumsporozoite protein
Gene (Uniprot):CSP
Chain IDs:G
Chain Length:397
Number of Molecules:1
Biological Source:Plasmodium falciparum (isolate 3D7)

UniProt ID:Q7K740 Pfam ID:PF00090

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:L9-21 heavy chain
Chain IDs:A (auth: H), C (auth: M), E (auth: O)
Chain Length:119
Number of Molecules:3
Biological Source:Homo sapiens

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:L9-21 light chain
Chain IDs:B (auth: L), D (auth: N), F (auth: P)
Chain Length:107
Number of Molecules:3
Biological Source:Homo sapiens

Ligand Molecules

Primary Citation

Cryo-EM structure of L9-21 in complex with Plasmodium falciparum circumsporozoite protein (PfCSP)

Tripathi, P, Kwong, P.D.Show

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Primary Citation of related structures

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