ISDA: 9YGH

Deposition Date 2025-09-28

Release Date 2026-08-05

Last Version Date 2026-08-05

Entry Detail

PDB ID:

9YGH

Keywords:

IMMUNE SYSTEM

Title:

Cryo-EM structure of L9-F4 in complex with Plasmodium falciparum circumsporozoite protein (PfCSP)

Biological Source:

Source Organism(s):

Plasmodium falciparum (isolate 3D7) (Taxon ID: 36329)
Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.83 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Circumsporozoite protein
Chain IDs:A (auth: G)
Chain Length:397
Number of Molecules:1
Biological Source:Plasmodium falciparum (isolate 3D7)

Polymer Type:polypeptide(L)
Molecule:L9-F4 heavy chain
Chain IDs:B (auth: H), D (auth: M), F (auth: O)
Chain Length:119
Number of Molecules:3
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:L9-F4 light chain
Chain IDs:C (auth: L), E (auth: N), G (auth: P)
Chain Length:107
Number of Molecules:3
Biological Source:Homo sapiens

Ligand Molecules

Primary Citation

Cryo-EM structure of L9-F4 in complex with Plasmodium falciparum circumsporozoite protein (PfCSP)

Tripathi, P, Kwong, P.D.Show

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Primary Citation of related structures

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