ISDA: 9YF0

Deposition Date 2025-09-24

Release Date 2026-08-05

Last Version Date 2026-08-05

Entry Detail

PDB ID:

9YF0

Keywords:

MEMBRANE PROTEIN

Title:

Human muscle nAChR SCCMS aV249F ACh, Fluoxetine bound

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.79 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Acetylcholine receptor subuni
Gene (Uniprot):CHRNA1
Mutagens:V249F
Chain IDs:A, B (auth: C)
Chain Length:437
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P02708 Pfam ID:PF02931, PF02932

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Acetylcholine receptor subuni
Gene (Uniprot):CHRNE
Chain IDs:E (auth: B)
Chain Length:473
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q04844 Pfam ID:PF02931, PF02932

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Acetylcholine receptor subuni
Gene (Uniprot):CHRND
Chain IDs:D
Chain Length:496
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q07001 Pfam ID:PF02931, PF02932

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Acetylcholine receptor subuni
Gene (Uniprot):CHRNB1
Chain IDs:C (auth: E)
Chain Length:478
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P11230 Pfam ID:PF02931, PF02932

Ligand Molecules