9YE6 image
Deposition Date 2025-09-23
Release Date 2026-08-05
Last Version Date 2026-08-05
Entry Detail
PDB ID:
9YE6
Title:
Human muscle nAChR FCCMS eP121L ACh-bound
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Method Details:
Experimental Method:
Resolution:
2.47 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Acetylcholine receptor subuni
Gene (Uniprot):CHRNA1
Chain IDs:A, B (auth: C)
Chain Length:437
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Acetylcholine receptor subuni
Gene (Uniprot):CHRNE
Mutagens:P121L
Chain IDs:E (auth: B)
Chain Length:473
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Acetylcholine receptor subuni
Gene (Uniprot):CHRND
Chain IDs:D
Chain Length:496
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Acetylcholine receptor subuni
Gene (Uniprot):CHRNB1
Chain IDs:C (auth: E)
Chain Length:480
Number of Molecules:1
Biological Source:Homo sapiens
Primary Citation
Correcting congenital myasthenia-associated acetylcholine receptor defects.
Nature ? ? ? (2026)
PMID: 42386970 DOI: 10.1038/s41586-026-10706-1
Primary Citation of related structures
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