ISDA: 9YDY

Deposition Date 2025-09-23

Release Date 2026-03-11

Last Version Date 2026-08-19

Entry Detail

PDB ID:

9YDY

Keywords:

PROTEIN BINDING

Title:

C-terminal coiled coil dimer of human TACC3

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.30 Å

R-Value Free:

0.26

R-Value Work:

0.24

R-Value Observed:

0.25

Space Group:

C 1 2 1

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Transforming acidic coiled-co
Gene (Uniprot):TACC3
Chain IDs:A, B
Chain Length:81
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q9Y6A5 Pfam ID:PF05010

Primary Citation

Context-dependent variability of HIF heterodimers influences interactions with macromolecular and small molecule partners.

Closson, J.D, Xu, X, Zhang, M, Tiyani, T.T, Marcelino, L.P, Isiorho, E.A, Nagati, J.S, Garcia, J.A, Gardner, K.H.Show

Proc.Natl.Acad.Sci.USA 123 e2514042123 e2514042123 (2026)

PMID: 42048441 DOI: 10.1073/pnas.2514042123

Primary Citation of related structures

Feedback Form