ISDA: 9YCW

Deposition Date 2025-09-19

Release Date 2026-05-20

Last Version Date 2026-05-20

Entry Detail

PDB ID:

9YCW

Keywords:

PROTEIN BINDING

Title:

Crystal structure of USP16 ZnF-UBP domain

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli 'bl21-gold(de3)plyss ag'

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.80 Å

R-Value Free:

0.17

R-Value Work:

0.13

R-Value Observed:

0.13

Space Group:

P 31

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Ubiquitin carboxyl-terminal h
Gene (Uniprot):USP16
Chain IDs:A, B, C
Chain Length:125
Number of Molecules:3
Biological Source:Homo sapiens

UniProt ID:Q9Y5T5 Pfam ID:PF02148 EC:3.4.19.12

Ligand Molecules

GOL

Primary Citation

The ZnF-UBP domain regulates USP16 activity by dislodging ubiquitin from the active site

Alexandrovics, J.A, Agrata, R, Schenk, P, Cerra, A, Nachbur, U, Babon, J.J, Komander, D.Show

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