ISDA: 9YAS

Deposition Date 2025-09-16

Release Date 2026-05-27

Last Version Date 2026-07-08

Entry Detail

PDB ID:

9YAS

Keywords:

ANTITOXIN

Title:

Rana catesbeiana saxiphilin mutant - Y558A:STX-C13-OBz (co-crystal)

Biological Source:

Source Organism(s):

Aquarana catesbeiana (Taxon ID: 8400)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.45 Å

R-Value Free:

0.28

R-Value Work:

0.24

R-Value Observed:

0.25

Space Group:

P 21 21 21

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Saxiphilin
Mutagens:Y558A
Chain IDs:A, B
Chain Length:853
Number of Molecules:2
Biological Source:Aquarana catesbeiana

UniProt ID:P31226

Ligand Molecules

A1CTG

Primary Citation

Saxiphilin is a broad-spectrum toxin sponge for C13-modified saxitoxins.

Zakrzewska, S, Chen, Z, Park, E.R, Bhaskar, R.G, Bedell, T.A, Du Bois, J, Minor Jr, D.L.Show

Structure ? ? ? (2026)

PMID: 42309055 DOI: 10.1016/j.str.2026.05.008

Primary Citation of related structures

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