9YAC image
Deposition Date 2025-09-15
Release Date 2026-08-05
Last Version Date 2026-08-05
Entry Detail
PDB ID:
9YAC
Keywords:
VIRAL PROTEIN
Title:
Measles Virus Fusion Glycoprotein Postfusion Core (T461I/N462S/N465S Variant)
Biological Source:
Source Organism(s):
Measles morbillivirus (Taxon ID: 11234)
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.63 Å
R-Value Free:
0.20
R-Value Work:
0.17
R-Value Observed:
0.17
Space Group:
P 3
9YAC validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Fusion glycoprotein F1 N-term
Gene (Uniprot):F
Chain IDs:A (auth: C), C (auth: A), E
Chain Length:50
Number of Molecules:3
Biological Source:Measles morbillivirus
UniProt ID:P69358
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Fusion glycoprotein F1 C-term
Gene (Uniprot):F
Mutagens:T461I, N462S, N465S variant, M487(NLE)
Chain IDs:B (auth: D), D (auth: B), F
Chain Length:38
Number of Molecules:3
Biological Source:Measles morbillivirus
UniProt ID:P69358
Ligand Molecules
MG
Primary Citation
Hyperfusogenic Mutations Destabilize the Postfusion Six-Helix Bundle of the Measles Virus Fusion Glycoprotein.
Biochemistry ? ? ? (2026)
PMID: 42485314 DOI: 10.1021/acs.biochem.6c00182
Primary Citation of related structures
9YAC
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