ISDA: 9Y7Y

Deposition Date 2025-09-11

Release Date 2026-09-16

Last Version Date 2026-09-16

Entry Detail

PDB ID:

9Y7Y

Keywords:

IMMUNE SYSTEM

Title:

KRAS-specific 24-246 TCR in complex with HLA-C*01:02 presenting KRAS G12V 9mer peptide (11-AVGVGKSAL-19)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens, Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.98 Å

R-Value Free:

0.28

R-Value Work:

0.25

R-Value Observed:

0.26

Space Group:

P 1 21 1

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:24-246 TCR alpha chain (TRAV1
Chain IDs:E (auth: A)
Chain Length:216
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:24-246 TCR beta chain (TRBV6-
Chain IDs:A (auth: B)
Chain Length:252
Number of Molecules:1
Biological Source:Homo sapiens

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:MHC class I antigen
Gene (Uniprot):HLA-C
Chain IDs:B (auth: C)
Chain Length:302
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:F6IQ93

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Beta-2-microglobulin
Gene (Uniprot):B2M
Chain IDs:C (auth: D)
Chain Length:100
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P61769 Pfam ID:PF07654

Polymer Type:polypeptide(L)
Molecule:KRAS G12V 9mer peptide
Chain IDs:D (auth: P)
Chain Length:9
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules