ISDA: 9Y7C

Deposition Date 2025-09-09

Release Date 2026-09-23

Last Version Date 2026-09-23

Entry Detail

PDB ID:

9Y7C

Keywords:

IMMUNE SYSTEM

Title:

HB3VAR03 CIDRa1.4 in complex with B57 and C50 fabs

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Plasmodium falciparum HB3 (Taxon ID: 137071)

Expression System(s):

Cricetulus griseus, Trichoplusia ni

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.40 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:PfEMP1
Gene (Uniprot):PFHG_05052
Chain IDs:E (auth: A)
Chain Length:0
Number of Molecules:1
Biological Source:Plasmodium falciparum HB3

UniProt ID:A0A0L7KL67 Pfam ID:PF15447, PF05424, PF22672, PF21807, PF03011

Polymer Type:polypeptide(L)
Molecule:C50 heavy chain
Chain IDs:C (auth: B)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:C50 light chain
Chain IDs:D (auth: C)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:B57 heavy chain
Chain IDs:A (auth: H)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:B57 light chain
Chain IDs:B (auth: L)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

Primary Citation

Structure of variant specific human monoclonal antibody B57 in complex with HB3VAR03 CIDRa1.4 PfEMP1 protein

Raghavan, S.S.R, Ward, A.B.Show

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Primary Citation of related structures

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