ISDA: 9Y5R

Deposition Date 2025-09-05

Release Date 2026-07-08

Last Version Date 2026-07-08

Entry Detail

PDB ID:

9Y5R

Keywords:

TRANSLATION

Title:

Eukaryotic translation initiation factor 2-B (eIF2B) bound to phosphorylated eIF2alpha (NTD)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.01 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Translation initiation factor
Gene (Uniprot):EIF2B5
Chain IDs:A, F (auth: B)
Chain Length:721
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q13144 Pfam ID:PF02020

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Translation initiation factor
Gene (Uniprot):EIF2B2
Chain IDs:B (auth: C), G (auth: D)
Chain Length:368
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P49770 Pfam ID:PF01008

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Translation initiation factor
Gene (Uniprot):EIF2B4
Chain IDs:C (auth: E), H (auth: F)
Chain Length:523
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q9UI10 Pfam ID:PF01008

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Translation initiation factor
Gene (Uniprot):EIF2B1
Chain IDs:D (auth: G), I (auth: H)
Chain Length:305
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q14232 Pfam ID:PF01008

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Translation initiation factor
Gene (Uniprot):EIF2B3
Chain IDs:E (auth: I), J
Chain Length:452
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q9NR50 Pfam ID:PF00483, PF25084

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Eukaryotic translation initia
Gene (Uniprot):EIF2S1
Chain IDs:K (auth: L), L (auth: M)
Chain Length:222
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P05198 Pfam ID:PF00575, PF07541 EC:3.6.5.3

Modified Residue