ISDA: 9Y41

Deposition Date 2025-09-02

Release Date 2026-05-06

Last Version Date 2026-05-06

Entry Detail

PDB ID:

9Y41

Keywords:

ANTIVIRAL PROTEIN

Title:

Crystal structure of hemagglutinin head domain from H1N1 Influenza A virus A/Victoria/2570/2019 bound to the 49_C09 antibody

Biological Source:

Source Organism(s):

Influenza A virus (Taxon ID: 11320)
Homo sapiens (Taxon ID: 9606)

Expression System(s):

Trichoplusia ni, Homo sapiens

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.89 Å

R-Value Free:

0.28

R-Value Work:

0.23

R-Value Observed:

0.23

Space Group:

P 1 21 1

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Hemagglutinin
Gene (Uniprot):HA
Chain IDs:A (auth: G), B (auth: C)
Chain Length:223
Number of Molecules:2
Biological Source:Influenza A virus

UniProt ID:A0A6M4YP75

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Antibody 49_C09 heavy chain
Chain IDs:C (auth: H), E (auth: A)
Chain Length:228
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:9Y41

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Antibody 49_C09 light chain
Chain IDs:D (auth: L), F (auth: B)
Chain Length:214
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:9Y41

Ligand Molecules

Primary Citation

Childhood immunological imprinting of cross-subtype antibodies targeting the hemagglutinin head domain of influenza viruses

Li, S.H, Wang, B, Jo, G, Mikelov, A, Atkinson, R.K, Sage, V.L, Furey, C, Ort, J.T, Ye, N.Q, Rotten, K, Joshi, S.A, Lee, J.Y, Pursell, T.A, Drapeau, E.M, Han, J, Caller, A.P, Collman, R.G, Monto, A.S, Martin, E.T, Lakdawala, S.S, Ward, A.B, Wilson, I.A, Boyd, S.D, Hensley, S.E.Show

Cell Host Microbe ? ? ? (2026)

DOI: 10.1016/j.chom.2026.04.004

Primary Citation of related structures

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